多模态MRI技术对早期前列腺癌的应用研究

发布时间：2018-01-06 15:42

本文关键词：多模态MRI技术对早期前列腺癌的应用研究　出处：《中国临床医学影像杂志》2017年02期 　论文类型：期刊论文

【摘要】：目的:探讨多模态MRI技术对早期前列腺癌的诊断价值。方法:收集行前列腺MRI检查的前列腺疾病患者100例,以病理学诊断为金标准,所有患者均行T_2WI、DWI和DCEI检查。组合上述3种检查形成以下4种方案:方案1:T_2WI;方案2:T_2WI+DWI;方案3:T_2WI+DCEI;方案4:T_2WI+DWI+DCEI。对影像与病理对照结果进行ROC曲线分析,Z检验比较各组方案的曲线下面积(AUC),并计算各组方案的敏感度、特异度和准确度。结果:4种检查方案中,方案4的诊断敏感度、特异度及准确度最高,分别为92.6%、87.0%及90%,方案1的诊断敏感度、特异度及准确度最低,分别为68.5%、63.0%及66%。各组方案AUC值从大到小依次为:方案4:0.916、方案2:0.908、方案3:0.870、方案1:0.697,方案1与方案2、方案3及方案4间的AUC值比较均有统计学差异(P0.05),方案2、方案3及方案4间两两比较AUC值均无统计学差异(P0.05)。结论:T_2WI+DWI,T_2WI+DCEI和T_2WI+DWI+DCEI对早期前列腺癌均有较高的诊断价值,其中T_2WI+DWI较T_2WI+DCEI临床应用价值更高,而T_2WI+DWI+DCEI诊断能力最强。
[Abstract]:Objective: to evaluate the value of multimodal MRI in the diagnosis of early prostate cancer. Methods: 100 patients with prostatic diseases were examined by MRI. All patients were examined by T2WIWI and DCEI. The above three kinds of examinations were combined to form the following four schemes: 1: TW 2WI; Plan 2: T2WI DWI; Plan 3: T2WI DCEI; Plan 4: T2WI DWI DCEI.The ROC curve analysis was performed to compare the area under the curve of each group. The sensitivity, specificity and accuracy of each group were calculated. Results the diagnostic sensitivity, specificity and accuracy of the four schemes were 92.67.0% and 90%, respectively. The diagnostic sensitivity, specificity and accuracy of scheme 1 were 68.5% and 63.0%, respectively. The AUC value of each group was 4: 0.916. Scheme 2: 0.908, scheme 3: 0.870, scheme 1: 0.697, the comparison of AUC between scheme 1 and scheme 2, scheme 3 and scheme 4 is statistically different (P0.05). There was no significant difference in AUC value between scheme 2, scheme 3 and scheme 4 (P 0.05). Conclusion\% T2WI DWI. Both T2WI DCEI and T2WI DWI DCEI have high diagnostic value for early prostate cancer. The clinical application value of T2WI DWI was higher than that of T 2WI DCEI, and the diagnosis ability of T2WI DWI DCEI was the strongest.
【作者单位】：南方医科大学珠江医院放射科;
【基金】：广东省医学科学技术研究基金资助项目(A2015291) 广东省科技计划资助项目(2014A020212665)
【分类号】：R737.25;R445.2
【正文快照】： 前列腺癌是男性泌尿生殖系统最常见的恶性肿瘤,在我国前列腺癌的发病率在近年来不断上升[1]。MRI是无创性检查前列腺癌的首选方法,由于T2WI、DWI、DCEI及MRSI等在单独应用于早期前列腺癌时有其局限性,综合多模态MRI技术,可以相互弥补和印证,但如何联合这些MRI技术,应用何种诊

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