脑膜瘤中ADC值、rADC值与Ki-67增殖指数的相关性分析

发布时间：2018-01-07 03:18

本文关键词：脑膜瘤中ADC值、rADC值与Ki-67增殖指数的相关性分析　出处：《临床放射学杂志》2017年01期 　论文类型：期刊论文

【摘要】：目的探讨脑膜瘤的表观扩散系数(ADC)值、相对表观扩散系数(rADC)值与Ki-67增殖指数的相关性,提高术前评估脑膜瘤复发风险的准确率。方法回顾性分析经病理证实且行Ki-67阳性率测定的47例脑膜瘤患者资料,术前均行常规MRI及DWI检查,测量肿瘤实质、肿瘤实质对侧镜面正常区的ADC及ADCwm值,计算rADC值(ADC/ADC_(wm))并分析ADC、rADC与Ki-67增殖指数的相关性。结果脑膜瘤的ADC值与Ki-67增殖指数呈负相关(r~2=0.33,P0.001),rADC值与Ki-67增殖指数也呈负相关(r~2=0.31,P0.001)。结论 ADC值、rADC值与Ki-67增殖指数的负相关关系对术前明确脑膜瘤的病理级别及手术方式的选择很有价值。
[Abstract]:Objective To investigate the correlation between the value of apparent diffusion coefficient ( ADC ) and the value of apparent diffusion coefficient ( rADC ) and Ki - 67 proliferation index , and to improve the accuracy of preoperative evaluation of the risk of recurrence . The correlation between ADC value and Ki - 67 proliferation index was analyzed retrospectively . Results The ADC value was negatively correlated with Ki - 67 proliferation index ( r ~ 2 = 0.33 , P0.001 ) , and the rADC value was negatively correlated with Ki - 67 proliferation index ( r ~ 2 = 0.31 , P 0.001 ) . Conclusion The negative correlation between ADC value , rADC value and Ki - 67 proliferation index is valuable for the preoperative diagnosis of the pathological grade and surgical mode .

【作者单位】：潍坊医学院医学影像学系;潍坊市人民医院放射科;潍坊市人民医院病理科;
【分类号】：R739.45;R445.2
【正文快照】： 脑膜瘤是最常见的脑膜起源肿瘤,占成人颅内肿瘤的35%[1]。大多数(90%)为低级别脑膜瘤,少数为高级别脑膜瘤。高级别脑膜瘤比低级别脑膜瘤有更高的复发风险。本研究探讨脑膜瘤表观扩散系数(ADC)、相对表观扩散系数(rA DC)与Ki-67增殖指数的相关关系,以期提高术前评估脑膜瘤复发

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