促胃肠动力药提高鼻肠管幽门后置管成功率的网状meta分析

发布时间：2018-02-23 18:35

本文关键词： 甲氧氯普胺红霉素多潘立酮促胃肠动力药幽门后置管网状meta分析　出处：《郑州大学学报(医学版)》2017年01期 　论文类型：期刊论文

【摘要】：目的:采用网状meta分析的方法比较甲氧氯普胺、红霉素和多潘立酮3种促胃肠动力药提高鼻肠管幽门后置管成功率的有效性。方法:计算机检索Cochrane Central Register of Controlled Trials、Pub Med、EMBASE、OVID、Web of Science、中国知网和万方数据库,检索时限为从各数据库建库至2015年10月。按纳入和排除标准进行文献筛选、资料提取及meta分析。结果:共纳入11篇文献,共计802例患者。直接meta分析结果显示,甲氧氯普胺(OR=2.37,95%CI=1.64~3.42,P0.001)、红霉素(OR=3.45,95%CI=2.05~5.81,P0.001)、多潘立酮(OR=3.62,95%CI=2.00~6.56,P0.001)在提高幽门后置管成功率方面疗效均优于安慰剂。排序概率图显示,红霉素效果最佳,其次是甲氧氯普胺和多潘立酮。结论:在提高鼻肠管幽门后置管成功率的促胃肠动力药中,红霉素的效果优于甲氧氯普胺和多潘立酮。
[Abstract]:Objective: to compare metoclopramide with reticular meta. Three gastrointestinal motility agents, erythromycin and domperidone, were used to improve the success rate of retropyloric tube placement in nasal and intestinal tubes. Methods: Cochrane Central Register of Controlled Trialsof Pub Medo EMBASEN OVIDE Web of Science, China knowledge Network and Wanfang database were searched by computer. The retrieval time was from the establishment of each database to October 2015. According to the criteria of inclusion and exclusion, literature selection, data extraction and meta analysis were carried out. Results: a total of 802 patients were included in 11 articles. The results of direct meta analysis showed that, The efficacy of OR2. 3795 CIQ 1.64 + 3.42 P0.001, erythromycin 3. 455 ~ 95 CIQ 2.055.81 P0.001, orpiperidone OR3. 62 ~ 95 CIQ 2.00 6.56 P0.001) was better than that of placebo in improving the success rate of posterior pyloric tube placement. The sequence probability diagram showed that erythromycin was the best. Conclusion: erythromycin is superior to metoclopramide and domperidone in improving the success rate of gastrointestinal motility drugs.
【作者单位】：郑州人民医院重症医学科;
【分类号】：R459.7

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