IVF-ET中内膜整理术对子宫内膜容受性影响的经阴道三维超声评价

发布时间：2018-03-03 14:01

本文选题：子宫内膜　切入点：超声检查　出处：《中国临床医学影像杂志》2017年02期 　论文类型：期刊论文

【摘要】：目的:应用经阴道三维超声评价子宫内膜整理术对体外受精-胚胎移植(IVF-ET)患者内膜容受性的影响,探讨内膜整理术对改善子宫内膜容受性,提高临床妊娠率的价值。方法:采集在我院IVF-ET反复失败3次以上且具有子宫内膜整理术的适应症患者103例,根据患者自愿原则,将其中施行子宫内膜整理手术的55例患者分为整理组,其余未做过子宫内膜整理术的48例患者分为未整理组。采用经阴道三维超声分别于HCG日、ET日检测两组患者子宫内膜厚度、容积、内膜及内膜下血流分布、血流参数(S蛐D、PI、RI、VI、FI、VFI),于2周后超声检查两组患者宫内情况并追踪妊娠结局。结果:整理组与未整理组一般情况无统计学差异(P0.05);HCG日、ET日子宫内膜容积、厚度无差异(P0.05),子宫内膜血流参数S蛐D、PI、RI均低于未整理组(P0.05);ET日整理组FI值高于未整理组(P0.05)。整理术前后ET日子宫内膜血流参数S蛐D、RI、FI有统计学差异(P0.05)。内膜整理组的种植成功率和临床妊娠率高于未整理组。结论 :子宫内膜整理术有助于改善子宫内膜及内膜下血流灌注,进而可以对提高胚胎种植率及临床妊娠成功率有帮助。
[Abstract]:Objective: to evaluate the effect of endometrial finishing on the endometrial receptivity of IVF-ETS patients with IVF-ETT by transvaginal three-dimensional ultrasound, and to explore the effect of endometrial finishing on the improvement of endometrial receptivity. Methods: the clinical pregnancy rate was improved in our hospital. Methods: 103 patients with indication of repeated failure of IVF-ET and endometrial finishing were collected according to the voluntary principle of the patients. 55 patients undergoing endometrial finishing were divided into finishing group and 48 patients without endometrial finishing were divided into untreated group. The thickness of endometrium was measured by transvaginal three-dimensional ultrasound on HCG day and et day, respectively. Volume, blood flow distribution of endometrium and subendometrial blood flow, blood flow parameter S / DII / Pi VIV VFI were examined by ultrasound 2 weeks later and pregnancy outcome was tracked. Results: there was no significant difference between the finishing group and the untreated group in the general situation of endometrial volume on the et day of P0.05HCG / et day endometrial volume, and the results showed that there was no significant difference between the two groups. There was no difference in thickness (P 0.05), and the RI of endometrial blood flow parameters (S / D) was lower than that of untreated group (P 0.05 / P 0.05). There was a significant difference in endometrial blood flow parameters S / D ~ (1) I ~ (I) (P _ (0.05)) before and after finishing. The species of endomembrane finishing group were different from that of untreated group (P _ (0.05)). The blood flow parameters (S / D) of endometrium were significantly higher than that of untreated group (P _ (0.05)). The success rate of implantation and clinical pregnancy rate were higher than that of untreated group. Conclusion: endometrial finishing can improve the blood flow perfusion of endometrium and subendometrium. Thus, it is helpful to improve embryo implantation rate and clinical pregnancy success rate.
【作者单位】：三峡大学仁和医院超声科;三峡大学医学院;
【基金】：湖北省宜昌市科技研究与开发项目(No:A12301-48)
【分类号】：R714.8;R445.1

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