超声光散射成像与PET-CT联合应用在乳腺癌诊断中的价值

发布时间：2018-03-04 23:18

本文选题：超声光散射成像　切入点：PET-CT　出处：《中国医学科学院学报》2017年05期 　论文类型：期刊论文

【摘要】：目的探讨超声光散射成像(DOT)与PET-CT联合应用在乳腺诊断中的价值。方法对38例患者的40个病灶分别进行DOT和PET-CT检查,与病理结果对照,对比分析DOT及PET-CT在乳腺癌超声诊断中的敏感性、特异性、准确性、阳性预测值、阴性预测值。结果 DOT对乳腺癌诊断的敏感性为78.26%,特异性为76.47%,准确性为77.50%,阳性预测值为72.22%,阴性预测值为81.81%。PET-CT对乳腺癌诊断的敏感性为86.96%,特异性为82.35%,准确性为85.00%,阳性预测值为86.96%,阴性预测值为82.35%。联合应用DOT和PET-CT的敏感性为86.96%,特异性为94.12%,准确性为90.00%,阳性预测值为95.23%,阴性预测值84.21%。结论 DOT和PET-CT检查均为有效的诊断方法,联合应用DOT和PET-CT可以提高乳腺癌的诊断效能,提高诊断特异性、阳性预测值及准确性,减少不必要的活检,对临床治疗方案的选择及患者的预后具有重要意义。
[Abstract]:Objective to evaluate the value of combined use of ultrasound light scattering imaging (dot) and PET-CT in the diagnosis of mammary gland. Methods 40 lesions of 38 patients were examined by DOT and PET-CT respectively, and the results were compared with pathological results. The sensitivity, specificity, accuracy and positive predictive value of DOT and PET-CT in ultrasonic diagnosis of breast cancer were compared and analyzed. Results the sensitivity of DOT to the diagnosis of breast cancer was 78.26, the specificity was 76.477.47, the accuracy was 77.50, the positive predictive value was 72.22, the negative predictive value was 81.81 and the sensitivity of PET-CT was 86.96, the specificity was 82.35, the accuracy was 85.00, the positive predictive value was 72.22, the negative predictive value was 81.81, the specificity was 82.35, and the accuracy was 85.00. The predictive value was 86.96 and the negative predictive value was 82.35.The sensitivity, specificity, accuracy, positive predictive value and negative predictive value of DOT and PET-CT were 86.96, 94.12, 90.002, 95.23 and 84.21, respectively. Conclusion both DOT and PET-CT are effective diagnostic methods. Combined use of DOT and PET-CT can improve the diagnostic efficacy, specificity, positive predictive value and accuracy of breast cancer, reduce unnecessary biopsy, and play an important role in the selection of clinical treatment schemes and the prognosis of patients.
【作者单位】：中国医学科学院北京协和医学院北京协和医院超声医学科;中国医学科学院北京协和医学院北京协和医院核医学科;中国医学科学院北京协和医学院北京协和医院乳腺外科;
【基金】：国家自然科学基金(81601517;81371557)~~
【分类号】：R445.1;R730.44;R737.9

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