胃肠道恶性肿瘤患者围手术期肠外营养的治疗效果

发布时间：2018-03-18 15:11

本文选题：胃肠道恶性肿瘤　切入点：围手术期肠外营养　出处：《东南大学学报(医学版)》2017年02期 　论文类型：期刊论文

【摘要】：目的:探讨围手术期肠外营养对胃肠道恶性肿瘤患者术后营养状况的干预效果。方法:胃肠道恶性肿瘤患者84例,按随机数字表法随机分为实验组与对照组,每组各42例。实验组术前7 d开始给予肠外营养,对照组常规给予糖电解质输液;两组患者均于术后第1天开始给予等氮等热量的肠外营养治疗,观察两组患者术前1 d、术后7 d各项指标的变化。结果:实验组患者术前1 d的体重指数(body mass index,BMI)值、血清前白蛋白(prealbumin,PA)和转铁蛋白(transferrin,TF)值均高于对照组,差异有统计学意义(P0.05)。术后7 d,实验组患者的BMI、肱三头肌皮褶厚度(triceps skinfold thickness,TSF)值、血白蛋白(albumin,ALB)、血红蛋白(hemoglobin,HGB)、PA和TF值均高于对照组,实验组肺部感染发生率低于对照组,差异均有统计学意义(P0.05)。结论:存在营养风险的胃肠道恶性肿瘤患者术前给予肠外营养治疗可有效改善患者术后的营养状况,降低术后肺部感染发生率。
[Abstract]:Objective: to investigate the effect of perioperative parenteral nutrition on postoperative nutritional status of patients with gastrointestinal malignancy. Methods: 84 patients with gastrointestinal malignancy were randomly divided into experimental group and control group according to random digital table. The experimental group received parenteral nutrition 7 days before operation, the control group received routine infusion of sugar and electrolyte, and the two groups received iso-nitrogen and equal caloric parenteral nutrition on the first day after operation. Results: the body mass index (BMI), serum albumin prealbumin (PAA) and transferrin transferrin (TFF) of the patients in the experimental group were higher than those in the control group 1 day before operation and 7 days after operation. On the 7th day after operation, the BMIs, triceps skinfold thicknessen, albumin albumin, hemoglobulin HGBP and TF of the patients in the experimental group were higher than those in the control group, and the incidence of pulmonary infection in the experimental group was lower than that in the control group. Conclusion: parenteral nutrition therapy can effectively improve the postoperative nutritional status and reduce the incidence of postoperative pulmonary infection in patients with gastrointestinal cancer with nutritional risk.
【作者单位】：承德医学院附属医院营养科;承德医学院附属医院静脉用药调配中心;承德医学院附属医院介入中心;承德医学院附属医院内分泌科;承德市中心医院放化疗中心;
【基金】：承德市科学技术研究与发展计划项目(20132062)
【分类号】：R459.3;R735

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