斑点追踪显像技术评价肥厚型心肌病患者心肌应变的研究

发布时间：2018-04-10 15:21

本文选题：二维斑点追踪 + 肥厚型心肌病　；参考：《中国现代医生》2017年06期

【摘要】：目的应用二维斑点追踪显像(2DSTI)技术评价肥厚型心肌病患者的心肌应变特点。方法选择正常对照组30例,肥厚型心肌病组30例。应用STI技术测定左心室各壁基底段、中间段和心尖段收缩期峰值应变(Ss),并对检测结果进行分析。结果与对照组比较,肥厚型心肌病组室间隔增厚(P0.05),肥厚型心肌病组心肌纵向应变值在左室基底段和中间段、心尖段均较对照组低(P0.05)。直线相关分析显示各组间LVEF与收缩期纵向峰值应变之间均存在正相关(r=0.589、0.797)。IVS在对照组与收缩期纵向峰值应变之间无明显相关性,但在肥厚型心肌病组与收缩期纵向峰值应变之间呈负相关(r=-0.538)。结论在肥厚型心肌病患者的整体左室收缩功能减低之前,其左室各节段心肌应变改变已经出现,STI可以发现患者早期局部左室功能的改变。肥厚型心肌病患者的收缩期峰值应变与其LVEF水平呈正相关,与IVS厚度呈负相关。应用二维斑点追踪显像技术测量肥厚型心肌病患者收缩期左室纵向应变值,有助于了解患者心脏收缩时心肌纵向运动和应变值的变化情况,能够判断和评价局部心肌功能。
[Abstract]:Objective to evaluate the characteristics of myocardial strain in hypertrophic cardiomyopathy by two-dimensional dot-tracing imaging (2 D STI).Methods 30 cases of normal control group and 30 cases of hypertrophic cardiomyopathy group were selected.The peak systolic strain of basal segment, middle segment and apical segment of left ventricle was measured by STI and the results were analyzed.Results compared with the control group, the ventricular septal thickening in hypertrophic cardiomyopathy group was significantly higher than that in the control group (P 0.05), and the longitudinal strain values in the left ventricular basal segment, middle segment and apical segment in the hypertrophic cardiomyopathy group were lower than those in the control group (P 0.05).Linear correlation analysis showed that there was a positive correlation between LVEF and peak systolic strain in each group. There was no significant correlation between the control group and the systolic peak strain.But in hypertrophic cardiomyopathy group, there was a negative correlation between peak strain of systolic phase and longitudinal peak strain.Conclusion before the whole left ventricular systolic function is decreased in patients with hypertrophic cardiomyopathy, the changes of myocardial strain in each segment of the left ventricle have already appeared. STI can detect the early changes of left ventricular function in patients with hypertrophic cardiomyopathy.Peak systolic strain was positively correlated with LVEF level and negatively correlated with IVS thickness in patients with hypertrophic cardiomyopathy.The measurement of left ventricular longitudinal strain in patients with hypertrophic cardiomyopathy by two dimensional speckle tracing imaging is helpful to understand the changes of longitudinal motion and strain value of myocardium during cardiac contraction and to judge and evaluate the regional myocardial function in patients with hypertrophic cardiomyopathy.
【作者单位】：福建医科大学附属福州市第一医院超声影像科;福建省立医院超声科;
【分类号】：R542.2;R445.1

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