常规腔内超声联合实时剪切波弹性成像评估宫颈癌放化疗疗效

发布时间：2018-04-22 14:22

本文选题：宫颈癌 + 放化疗　；参考：《中国超声医学杂志》2017年07期

【摘要】：目的探讨腔内常规超声联合实时剪切波弹性超声成像技术评价对宫颈癌放化疗后疗效的应用价值。方法对在我院经病理确诊为宫颈癌的患者20例,分别于放化疗前后进行超声检查,经阴道常规超声测量治疗前后宫颈癌病灶大小,记录其血供状况;剪切波弹性超声成像测量治疗前后病灶区域的弹性模量绝对数值,包括平均值、最大值及最小值。结果放化疗前宫颈正常结构消失,宫颈内多可见低回声结构,血流信号丰富;放化疗后宫颈形态多恢复正常,宫颈内低回声结构减小或消失,边界模糊不清,血流信号减少。治疗前肿物剪切波弹性最大值、最小值及平均值分别为(219.4±76.3)kPa、(148.1±68.6)kPa、(183.5±79.9)kPa,治疗后肿物弹性最大值、最小值及平均值分别为(139.3±65.2)kPa、(80.2±35.9)kPa、(111.4±51.7)kPa。治疗前后肿物弹性最大值、最小值及平均值间差异均具有统计学意义(P0.001)。结论常规腔内超声联合实时剪切波弹性成像可以为宫颈癌的临床疗效评价提供有价值的信息。
[Abstract]:Objective to evaluate the efficacy of intracavitary conventional ultrasound combined with real-time shear wave elastography in the treatment of cervical cancer after radiotherapy and chemotherapy. Methods Twenty patients with cervical cancer diagnosed by pathology in our hospital were examined by ultrasound before and after radiotherapy and chemotherapy. The size of cervical cancer was measured by conventional transvaginal ultrasound before and after treatment, and the blood supply was recorded. The absolute values of elastic modulus of the lesion were measured by shear wave elastography before and after treatment, including mean value, maximum value and minimum value. Results the normal structure of the cervix disappeared before radiotherapy and chemotherapy, the hyperechoic structure in the cervix was mostly seen in the cervix, the blood flow signal was abundant, the shape of the cervix returned to normal, the hypoechoic structure of the cervix decreased or disappeared, the boundary was blurred and the blood flow signal decreased. Before treatment, the maximum value of shear wave elasticity, the minimum value and the average value were 219.4 卤76.3kPa.148.1 卤68.6kPa.183.5 卤79.9kPa.After treatment, the maximum value, minimum value and mean value of the tumor elasticity were 139.3 卤65.2kPa-80.2 卤35.9kPa.111.4 卤51.7kPa. The difference of the maximum, minimum and average values of tumor elasticity before and after treatment was statistically significant (P 0.001). Conclusion conventional intracavitary ultrasound combined with real-time shear wave elastography can provide valuable information for clinical evaluation of cervical cancer.
【作者单位】：解放军总医院第一附属医院超声科;解放军总医院第一附属医院妇产科;
【分类号】：R445.1;R737.33

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