CT引导下适形冷冻消融治疗溶骨性转移瘤

发布时间：2018-04-23 03:39

本文选题：骨肿瘤 + 体层摄影术　；参考：《中国介入影像与治疗学》2017年02期

【摘要】：目的评估CT引导下适形冷冻消融治疗溶骨性转移瘤的安全性及局部疗效。方法收集在我院就诊的溶骨性骨转移瘤患者36例(共51处病灶),所有患者均有明确的病理诊断且经双膦酸盐类药物治疗2个月后疼痛无缓解。患者均接受CT引导下适形冷冻消融治疗,并于治疗后即刻、2个月后分别行增强CT检查以评估治疗效果及观察有无并发症。分析患者在术前、术后1周及术后2个月的视觉模拟评分系统(VAS)疼痛评分结果。结果所有患者顺利完成手术,未出现严重并发症。治疗后2个月均未见局部复发、增强CT均未见强化;2例患者出现新发转移灶。患者术后1周[(4.18±0.82)分]及2个月[(2.36±1.01)分]VAS疼痛评分均较术前[(7.13±1.55)分]下降(P均0.05)。结论 CT引导下适形冷冻治疗溶骨性转移瘤局部疗效显著、安全性较高。
[Abstract]:Objective to evaluate the safety and local efficacy of CT-guided conformal cryoablation for osteolytic metastases. Methods 36 patients (51 lesions) with osteolytic bone metastases were collected. All patients had definite pathological diagnosis and the pain was not alleviated after 2 months of treatment with bisphosphonates. All patients were treated with CT guided conformal cryoablation, and enhanced CT was performed immediately after treatment and 2 months later to evaluate the therapeutic effect and observe the complications. The visual analogue scoring system (VAS) was used to evaluate the pain scores of the patients before, 1 week and 2 months after operation. Results all patients successfully completed the operation without serious complications. Two months after treatment, no local recurrence was found, and no new metastatic foci were found on enhanced CT in 2 cases. The VAS pain score at 1 week after operation [4.18 卤0.82) and 2 months [2.36 卤1.01] was significantly lower than that before operation (7.13 卤1.55) (P < 0.05). Conclusion CT-guided conformal cryotherapy for osteolytic metastases is effective and safe.
【作者单位】：中国人民解放军总医院放射科;
【基金】：国家自然科学基金项目(81271674)
【分类号】：R738.1;R730.44

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