血栓弹力图预测静脉血栓栓塞症发生的价值分析

发布时间：2018-04-23 11:29

本文选题：静脉血栓栓塞症 + 血栓弹力图　；参考：《中国实验血液学杂志》2017年05期

【摘要】：目的:系统搜集有关血栓弹力图预测静脉血栓栓塞症(venous thromboembolism,VTE)的临床研究文献,评价血栓弹力图在预测血栓发生事件中的应用价值。方法:计算机检索Pub Med,Central,Embase数据库中的相关临床实验研究文献,并手工检索相关参考文献,然后运用QUADAS-2工具对纳入文献的质量进行评价,最终对纳入的研究进行定性分析。结果:共纳入研究15篇,涉及293名VTE患者。纳入文献的质量及血栓弹力图预测VTE的准确性参差不齐。三分之二的研究显示,血栓弹力图参数的变化可以预测VTE的发生。结论:目前的研究显示,血栓弹力图预测VTE的准确性差异较大。血栓弹力图联合血栓与止血的其它实验室检测指标可能会提高预测VTE发生的准确性。
[Abstract]:Objective: to collect the clinical literatures on thromboelastography in predicting venous thromboembolism (VTE) and evaluate the value of thromboelastography in predicting thromboembolism. Methods: the relevant clinical experimental literatures were searched by computer in Pub Meden Central Embase database, and the related references were retrieved manually. Then the quality of the included documents was evaluated by QUADAS-2 tool, and the qualitative analysis of the included research was carried out. Results: a total of 15 studies involving 293 patients with VTE were included. The quality of the literature and the accuracy of thromboelastography in predicting VTE were uneven. The 2/3 study showed that changes in thromboelastic parameters could predict the occurrence of VTE. Conclusion: the accuracy of thromboelastogram in predicting VTE is quite different. Thromboelastography combined with other laboratory markers of thromboembolism and hemostasis may improve the accuracy of predicting the occurrence of VTE.
【作者单位】：郑州大学第一附属医院检验科河南省检验医学重点实验室;
【基金】：河南省科技攻关计划项目(152102410067;162102310142) 河南省教育厅科学技术研究重点项目(13A310622)
【分类号】：R446.11;R543.6

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