耐碳青霉烯类鲍曼不动杆菌目标性监测

发布时间：2018-06-11 18:27

本文选题：鲍曼不动杆菌 + 耐碳青霉烯鲍曼不动杆菌　；参考：《中国感染控制杂志》2017年07期

【摘要】：目的了解耐碳青霉烯类鲍曼不动杆菌(CRAB)的临床分布和耐药特征。方法回顾性分析某院2015年1—12月所有住院患者送检标本CRAB检出情况,分析其药敏试验结果。结果 721株AB中检出CRAB231株,CRAB检出率为32.04%。1—4季度中每季度CRAB的检出率分别为48.99%(73/149)、41.98%(68/162)、27.39%(63/230)、15.00%(27/180),呈下降趋势(P0.001)。CRAB主要来源于痰标本(140株,60.61%),其次是创面分泌物(33株,14.28%)和尿标本(24株,10.39%)。CRAB主要来源科室为重症监护病房(101株,43.72%)、神经外科(37株,16.02%)及烧伤整形科(22株,9.52%)。CRAB对氨苄西林/舒巴坦、庆大霉素、左氧氟沙星、环丙沙星的耐药率为85.28%~90.48%,对妥布霉素的耐药率较低(19.48%),未发现对多粘菌素B耐药的菌株。结论 CRAB耐药性较为严重,应针对重点科室进行重点管理,采取科学防控举措,有效减少医院感染事件的发生。
[Abstract]:Objective to investigate the clinical distribution and drug resistance characteristics of acinetobacter baumannii resistant to carbapenem. Methods the detection of CRAB in all inpatients in a hospital from January to December 2015 was analyzed retrospectively, and the results of drug sensitivity test were analyzed. Results in 721 strains of AB, the positive rate of CRAB231 strain CRAB was 32.04.1-4 quarterly CRAB detection rate was 48.99%, respectively, and the detection rate of CRAB in each quarter was 48.99%. The detection rate of CRAB231 strain was 41.98%. The results were as follows: 101 strains in intensive care unit, 37 strains in neurosurgery department and 22 strains in burn plastic surgery department were treated with ampicillin / sulbactam. The resistance rate of gentamicin, levofloxacin and ciprofloxacin was 85.28%, 90.48% and 19.48% respectively. Conclusion the drug resistance of CRAB is more serious, so we should focus on the management of key departments and take scientific measures to prevent and control the nosocomial infection in order to effectively reduce the incidence of nosocomial infection.
【作者单位】：苏北人民医院;
【基金】：国家自然科学基金(NO:81400899)
【分类号】：R446.5

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