动脉自旋标记MRI评价肾癌部分切除术后残余肾功能的价值

发布时间：2018-07-29 21:11

【摘要】：目的探讨动脉自旋标记(ASL)评估肾癌患者腹腔镜肾部分切除术后残余肾功能的价值。资料与方法前瞻性地研究15例行腹腔镜肾部分切除术的肾癌患者,于术前1周内及术后3个月行ASL扫描,分析ASL测得健侧肾皮质的肾血流量(RBF)值与放射性核素法测得肾小球滤过率的相关性,比较术前及术后3个月患侧、健侧肾组织RBF值的差异。结果健侧肾皮质RBF值与肾小球滤过率呈正相关(r=0.638,P0.05)。患侧残余肾组织RBF值[(291.5±37.3)ml/(100 g·min)]较术前肾组织RBF值[(237.8±46.2)/(100 g·min)]升高约53.7 ml/(100 g·min)(P0.05);健侧肾组织RBF值[(241.1±50.3)ml/(100 g·min)]较术前肾组织RBF值[(290.4±51.8)ml/(100 g·min)]下降约49.3 ml/(100 g·min)(P0.05)。结论ASL可以用来评价肾功能,且对评估腹腔镜肾癌部分切除术后残余肾血流灌注功能具有一定的价值。
[Abstract]:Objective to evaluate the value of arterial spin labeling (ASL) in evaluating residual renal function in patients with renal cell carcinoma after laparoscopic partial nephrectomy. Materials and methods Fifteen patients with renal cell carcinoma undergoing laparoscopic partial nephrectomy were studied prospectively. ASL scans were performed 1 week before operation and 3 months after operation. To analyze the correlation between renal blood flow (RBF) value measured by ASL and glomerular filtration rate (GFR) measured by radionuclide method, and to compare the difference of RBF value between preoperation and 3 months after operation. Results there was a positive correlation between RBF value and glomerular filtration rate (P 0.05). The RBF value of residual renal tissue [(291.5 卤37.3) ml/ (100 g min)] increased about 53.7 ml/ (100 g min) (P0.05) compared with the preoperative RBF value of renal tissue [(237.8 卤46.2) / (100 g min)], and the RBF value of healthy renal tissue [(241.1 卤50.3) ml/ (100g min)] decreased about 49.3 ml/ (100g min) (P0.05) compared with the preoperative RBF value of renal tissue [(290.4 卤51.8) ml/ (100g min)]. Conclusion ASL can be used to evaluate renal function and evaluate residual renal perfusion function after partial resection of Laparoscopic RCC.
【作者单位】：天津医科大学第一中心临床学院;
【分类号】：R445.2;R737.11

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