健康管理对颈动脉狭窄患者血脂水平及颈动脉斑块的影响

发布时间：2018-11-18 09:22

【摘要】：目的探讨健康管理对颈动脉狭窄患者血脂水平及颈动脉斑块的影响。方法将180例颈动脉狭窄患者分为健康管理组(90例)及常规治疗组(90例)。两组均给予常规治疗,健康管理组进行连续12个月的健康管理。于治疗前及治疗后第6、12个月检测患者的总胆固醇(TC)、三酰甘油(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋自胆固醇(LDL-C)水平;采用颈动脉彩色多普勒超声检测其颈动脉情况。结果健康管理组及常规治疗组治疗第6、12个月TC、TG、LDL-C水平显著低于治疗前,HDL-C水平显著升高(均P0.05)。两组间治疗前及治疗第6个月TC、TG、HDL-C及LDL-C水平差异无统计学意义(均P0.05)。健康管理组治疗第12个月TC、TG及LDL-C水平较常规治疗组显著降低,HDL-C水平显著升高(均P0.05)。健康管理组及常规治疗组治疗前与治疗第6个月Crouse斑块积分差异无统计学意义(均P0.05)。健康管理组治疗第12个月Crouse斑块积分显著低于治疗前(均P0.05)。两组间治疗前及治疗第6个月Crouse斑块积分差异无统计学意义(均P0.05)。健康管理组治疗第12个月Crouse斑块积分显著低于常规治疗组(P0.05)。结论长期健康管理干预可以降低颈动脉狭窄患者的血脂水平,改善颈动脉斑块情况。
[Abstract]:Objective to investigate the effect of health management on blood lipid level and carotid plaque in patients with carotid artery stenosis. Methods 180 patients with carotid artery stenosis were divided into health management group (90 cases) and routine treatment group (90 cases). Both groups were given routine treatment, the health management group for 12 months of continuous health management. The levels of total cholesterol (TC), triglyceride (TG), high density lipoprotein cholesterol (HDL-C) and low density egg self cholesterol (LDL-C) were measured before and 6 and 12 months after treatment. Carotid artery was detected by color Doppler ultrasound. Results the level of TC,TG,LDL-C in health management group and routine treatment group was significantly lower than that before treatment at the 6th and 12th month (P0.05). There was no significant difference in TC,TG,HDL-C and LDL-C levels between the two groups before and after treatment (P0.05). The levels of TC,TG and LDL-C in the health management group were significantly lower than those in the routine treatment group at the 12th month after treatment (P0.05). There was no significant difference in Crouse plaque score between health management group and routine treatment group before treatment and 6 months after treatment (P0.05). The score of Crouse plaque in the health management group was significantly lower than that before treatment at the 12th month (P0.05). There was no significant difference in Crouse plaque score between the two groups before and after treatment (P0.05). The score of Crouse plaque in the health management group was significantly lower than that in the routine treatment group at 12 months (P0.05). Conclusion long-term health management intervention can reduce blood lipid level and improve carotid plaque in patients with carotid artery stenosis.
【作者单位】：南京医科大学附属脑科医院《临床神经病学杂志》编辑部;南京大学医学院附属金陵医院(南京总医院)干部神经内科;
【基金】：总后保健专项课题(15BJZ10)
【分类号】：R473.74

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