平板运动试验综合指标对冠心病心肌缺血的诊断价值
[Abstract]:Objective: to study the relationship between multiple indexes of treadmill exercise test and myocardial ischemia of coronary heart disease (CHD), and to explore the diagnostic value of treadmill exercise test in myocardial ischemia of coronary heart disease (CHD). Methods: 464 patients with suspected coronary heart disease who underwent treadmill exercise test and coronary angiography within half a year were analyzed retrospectively. The changes of P wave duration before and after exercise, QRS wave group duration before and after exercise, R angle before and after exercise, U slope before and after exercise were analyzed by logistic regression method. The changes of R wave amplitude before and after exercise, S wave amplitude before and after exercise, ST segment before and after exercise, T wave amplitude before and after exercise, systolic blood pressure before and after exercise, Systolic blood pressure recovery ratio before and after exercise, diastolic blood pressure before and after exercise, heart rate recovery before and after exercise, exercise grade, symptoms during exercise) and coronary heart disease risk factors (sex, age, history of smoking, history of hypertension, history of hyperlipidemia), Diabetes history, family history of cardiovascular disease) to find out the diagnostic significance of coronary heart disease myocardial ischemia indicators, through discriminant analysis, the establishment of these indicators discriminant function, Then the discriminant function is verified by stepwise regression discriminant analysis. The difference between the discriminant function and the traditional positive index and single ST segment in the diagnosis of myocardial ischemia was analyzed and compared. Results: (1) Sex, age, history of diabetes, P, QRS, U, R, ST, T, R SBP and symptoms were statistically significant in the diagnosis of myocardial ischemia (P0.05). (2) the discriminant function equation was established as follows: Y=-1.158X1 0.024X2 1.342X3 0.023X4 0.049X5-0.083X6 1.461X7-3. 977X8 0.992X9 2.285X10 0.396X11-2.024. The correct rate of discriminant to positive group was 79.0%, and that of negative group was 82.8%. The total correct rate of discrimination was 81.5%. (3) the discriminant function showed that the discriminant function had a correct rate of 67 for the positive group and 90.9 for the negative group. (4) the sensitivity of the single ST segment depression to the diagnosis of myocardial ischemia was 79.0 and 69.5, and the specificity was 82.8% and 61.9%, respectively. (4) the discriminant function, the traditional positive index, and the single ST segment depression had a sensitivity of 79.0 and 69.1% in the diagnosis of myocardial ischemia, and the specificity was 82.8%, 61.9% and 66.2%, respectively. The positive predictive value was 71.1 and the positive predictive value was 49.3. The negative predictive value was 88.0 and the negative predictive value was 78.9. (5) the sensitivity, specificity, accuracy and positive predictive value of discriminant function in diagnosing myocardial ischemia of coronary heart disease were statistically significant compared with traditional indexes and ST segment depression (P0.05). There was no significant difference in negative predictive value (P0.05). (6) between the discriminant function and ST segment depression, the false positive rate of diagnosis of male coronary heart disease patients was not statistically significant (P0.05). The false positive rate in diagnosis of female patients was statistically significant (P0.05). (7) discriminant function and ST segment depression diagnosis single, three vessel disease false negative rate was not statistically significant (P0.05), The false negative rate in the diagnosis of double vessel disease was statistically significant (P0.05). Conclusion: (1) after exercise, the duration of P wave and QRS wave group widens, U slope decreases, and the amplitude of R wave and T wave increases. The increase of systolic blood pressure recovery ratio and chest pain have diagnostic significance for myocardial ischemia of coronary heart disease. (2) the comprehensive indexes can improve the sensitivity and specificity of treadmill exercise test in the diagnosis of coronary heart disease myocardial ischemia. (3) the discriminant function can improve the sensitivity of treadmill exercise stress test in the diagnosis of female coronary heart disease, (4) the discriminant function can reduce the missed diagnosis rate of double vessel disease in treadmill exercise test.
【学位授予单位】:遵义医学院
【学位级别】:硕士
【学位授予年份】:2017
【分类号】:R541.4;R540.41
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