生长抑素对老年术后早期炎性肠梗阻患者炎性因子及胃肠功能的影响

发布时间：2018-12-05 19:51

【摘要】：目的探讨生长抑素对老年术后早期炎性肠梗阻患者炎性因子及胃肠功能的影响。方法选择2014年2月至2015年7月收治的98例老年早期炎性肠梗阻患者为研究对象,采用随机数字表法分为对照组和观察组各49例。对照组给予常规治疗,观察组联合生长抑素施他宁治疗,比较两组治疗后临床疗效、胃肠功能、炎性因子等。结果观察组总有效率(91.84%)明显高于对照组(73.47%),差异有统计学意义(χ2=4.555,P0.05);肛门恢复排气、腹部症状缓解、肠鸣音恢复、治愈的时间均明显短于对照组(t=3.382、4.786、4.516、4.868,P0.05);血清C-反应蛋白、肿瘤坏死因子、白细胞介素-6水平明显低于对照组(t=7.492、8.723、8.253,P0.05)。结论联合生长抑素治疗有助于促进老年术后早期炎性肠梗阻患者胃肠功能恢复,减少肠道炎性反应,提高临床治疗效果。
[Abstract]:Objective to investigate the effects of somatostatin on inflammatory factors and gastrointestinal function in elderly patients with early postoperative inflammatory intestinal obstruction. Methods Ninety-eight elderly patients with early inflammatory intestinal obstruction from February 2014 to July 2015 were randomly divided into two groups: control group (n = 49) and observation group (n = 49). The control group was treated with routine therapy, the observation group was treated with somatostatin, and the clinical efficacy, gastrointestinal function and inflammatory factors were compared between the two groups. Results the total effective rate in the observation group (91.84%) was significantly higher than that in the control group (73.47%), and the difference was statistically significant (蠂 ~ 2 / 4.555P ~ (0.05). The recovery time of anal exhaust, abdominal symptoms and bowel sounds were significantly shorter than that of the control group (P 0.05), which were significantly shorter than those in the control group (t = 3.382, 4.786N, 4.516U, 4.868, P 0.05). The levels of serum C-reactive protein, tumor necrosis factor and interleukin-6 were significantly lower than those in the control group (t = 7.492, 8.723, 8.253, P 0.05). Conclusion the combination of somatostatin therapy can promote the recovery of gastrointestinal function, reduce the inflammatory reaction and improve the clinical effect in the elderly patients with early postoperative inflammatory intestinal obstruction.
【作者单位】：河北省唐山市人民医院普外科;
【基金】：唐山市科学技术研究与发展指导计划(06134601c-16)
【分类号】：R473.6

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