白血病患者PICC相关性血流感染目标性监测及危险因素分析

发布时间：2018-12-15 19:28

【摘要】：目的探讨白血病患者外周中心静脉导管(PICC)相关性血流感染的危险因素。方法选择2015年6月-2016年12月医院收治的白血病PICC置管患者150例,统计PICC相关性血流感染患者临床资料,经单因素及Logistic多因素分析,探讨PICC置管后发生相关性血流感染的危险因素。结果 150例患者中出现导管相关性血流感染20例,感染率13.33%,共检出病原菌20株,其中革兰阴性菌10株占50.00%,以肺炎克雷伯菌和大肠埃希菌为主;革兰阳性菌10株占50.00%,以表皮葡萄球菌为主;多因素logistic回归分析结果显示,年龄≥65岁、外周血象2.0×10~9/L、穿刺次数≥6次、化疗次数≥11次、留置时间≥11个月、伴有糖尿病是PICC导管相关性血流感染的独立危险因素(P0.05)。结论导致白血病患者PICC相关性血流感染的原因较多,应针对危险因素,化疗前应积极处理合并症,选择合理的导管种类、穿刺和封管方式,根据药敏试验科学使用抗菌药物,缩短置管时间,从而减少PICC相关性血流感染风险。
[Abstract]:Objective to investigate the risk factors of peripheral central venous catheter (PICC) associated blood flow infection in patients with leukemia. Methods from June 2015 to December 2016, 150 patients with leukemia PICC catheterization were selected. The clinical data of patients with PICC associated blood flow infection were analyzed by univariate and Logistic multivariate analysis. To investigate the risk factors of associated blood flow infection after PICC catheterization. Results among 150 patients, 20 cases had catheter-related blood flow infection, the infection rate was 13.33%. A total of 20 strains of pathogenic bacteria were detected, of which 10 strains were Gram-negative bacteria, mainly Klebsiella pneumoniae and Escherichia coli. Gram-positive bacteria accounted for 50.00m, mainly Staphylococcus epidermidis. Multivariate logistic regression analysis showed that age 鈮，

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