动态反应池-电感耦合等离子体质谱法同时测定尿液中17种元素

发布时间：2019-03-20 15:06

【摘要】：尿液样品用硝酸酸化至硝酸的体积分数为1%,离心后,上清液用4%(体积分数)硝酸溶液稀释10倍。采用动态反应池-电感耦合等离子体质谱法同时测定其中铅、镉、砷、硒、锰、铜、锌、锑、铍、钒、铁、镍、钼、铬、铊、钴、锡等17种元素的含量。以~(45)Sc(测定锰、铜、铍、钒、铁、镍、铬、钴)、~(72)Ge(测定砷、硒、锌)、115In(测定镉、锑、钼、锡)、~(209)Bi(测定铅、铊)为内标物。铁的线性范围在5.00mg·L~(-1)以内,其余元素的线性范围均在50.0μg·L~(-1)以内,检出限(3s)为0.000 5~0.496 0μg·L~(-1)。方法用于尿液样品的分析,加标回收率为85.6%~110%,测定值的相对标准偏差(n=7)为0.68%~4.8%。
[Abstract]:The urine sample was acidified by nitric acid to nitric acid by 1% volume fraction. After centrifugation, the supernatant was diluted 10 times with 4% (volume fraction) nitric acid solution. Simultaneous determination of 17 elements in lead, cadmium, arsenic, selenium, manganese, copper, zinc, antimony, beryllium, vanadium, iron, nickel, molybdenum, chromium, thallium, cobalt and tin by dynamic reaction cell-inductively coupled plasma mass spectrometry. Manganese, copper, beryllium, vanadium, iron, nickel, chromium and cobalt were determined by ~ (45) Sc (), ~ (72) Ge () determination of arsenic, selenium, zinc, 115In (determination of cadmium, antimony, molybdenum, tin) and ~ (209) Bi () determination of lead and thallium as internal standard. The linear range of iron is within 5.00mg 路L ~ (- 1), the linear range of other elements is within 50.0 渭 g 路L ~ (- 1), the detection limit (3s) is 0.000 渭 g 路L ~ (- 1). The method was applied to the analysis of urine samples. The recovery rate was 85.6% ~ 110%, and the relative standard deviation (n = 7) was 0.68% ~ 4.8%.
【作者单位】： 广西壮族自治区疾病预防控制中心;
【基金】：广西壮族自治区科技开发课题(桂科攻1298004-1) 广西医疗卫生重点科研课题(重2012053) 广西疾控中心青年基金课题(GXCDC201503)
【分类号】：O657.63;R446.12
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