二例类孟买型血型的血清学鉴定及输血实践

发布时间：2019-04-11 06:27

【摘要】：目的探讨类孟买型血型血清学鉴定方法及输血应对措施,为类孟买型鉴定和输血提供参考。方法利用吸收放散试验、血型物质中和抑制试验、微柱凝胶法等血型血清学方法鉴定患者、献血者ABO、H、Lewis血型及配血。结果 2例患者及2例献血者红细胞上常规方法未检测到ABH抗原,吸收放散试验能检测到ABH抗原,唾液分别测出ABH物质,1例Lewis血型检测为Le(a-b+),另外3例Lewis血型检测为Le(a-b-),其中2例证实为类孟买型Oh~A-分泌型,另外2例证实为Oh~B-分泌型。病例1能与普通B型相配合,病例2不能与普通A型相配合,但分别能与同型O_(HmA)和异型O_(HmB)相配合。结论类孟买型的正确鉴定及采取与合适的血液相配合输注,甚至与异型孟买型相配合输注,是类孟买型输血的必要应对措施。
[Abstract]:Objective to explore the methods of serological identification of similar Bombay type and the corresponding measures of blood transfusion, so as to provide reference for the identification of similar Bombay type and blood transfusion. Methods Blood group serological methods such as absorption-elution test, neutralization inhibition test and microcolumn gel method were used to identify ABO,H,Lewis blood group and blood matching of blood donors. Results ABH antigen was not detected in red blood cells of 2 patients and 2 blood donors. ABH antigen was detected by absorption-elution test. ABH substance was detected in saliva. One case of Lewis blood group was detected as Le. The other 3 cases of Lewis blood group were detected as Le, 2 of them were proved to be Bombay-like Oh~A- secretory type, and the other 2 cases were confirmed as Oh~B- secreting type. Case 1 can cooperate with normal type B, case 2 can not cooperate with common type A, but it can be matched with the same type of O _ (HmA) and the same type of O _ (HmB), respectively. Conclusion the correct identification of quasi-Bombay type and the combination infusion with suitable blood and even with hetero-Bombay type are the necessary countermeasures for similar Bombay type blood transfusion.
【作者单位】：文山州中心血站;文山州人民医院;
【基金】：文山州学科带头人培养对象项目支持(文科创人培办发[2015]1号)
【分类号】：R457.1

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