团体干预对耐多药肺结核患者治疗效果的影响

发布时间：2019-04-23 12:34

【摘要】：目的探讨团体干预对耐多药肺结核患者治疗效果的影响。方法采用便利抽样法,选取2012年5月~2015年8月云南省结核病临床治疗中心治疗的125例耐多药肺结核患者,以小组活动的形式进行团体干预,收集社会统计学资料、患者疾病相关资料、参与干预活动情况、治疗效果等资料,对影响耐多药肺结核预后的相关因素进行单因素分析和多因素回归分析,P0.05为差异有统计学意义。结果 125例患者中,治疗成功39例(31.2%);治疗中57例(45.6%);未治疗成功29例(23.2%)。单因素分析显示:年龄、职业、婚姻状况、团体干预是影响耐多药肺结核转归的相关因素,差异有统计学意义。多因素回归分析发现,参与团体干预(0次和4次:Waldx~2=13.333,P0.01,OR=4.315,95%CI=3.672~74.813)、性别(男和女:Waldx~2=5.248,P0.05,OR=-0.146,95%CI=0.152~-0.864)是耐药肺结核患者治疗效果的主要影响因素。并且数据显示,患者参加团体干预频次数越多,其服药依从性更好,能更客观地评估不良反应的严重程度,(x~2=33.82,P0.01;x~2=13.96,P0.01)。结论在耐多药肺结核患者的治疗过程中,坚持参加团体干预对改善耐多药结核病的预后、提高治愈率有促进作用。
[Abstract]:Objective to investigate the effect of group intervention on the treatment of multi-drug resistant pulmonary tuberculosis (MDR-TB). Methods 125 patients with MDR-TB were selected from May 2012 to August 2015 in Yunnan Provincial Tuberculosis Clinical treatment Center by means of convenient sampling. Group intervention was carried out in the form of group activities to collect social statistical data. The data of disease, intervention activities, therapeutic effect and so on were analyzed by univariate analysis and multivariate regression analysis on the related factors of prognosis of MDR-TB. The difference was statistically significant (P0.05). Results among 125 cases, 39 cases (31.2%) were successfully treated, 57 cases (45.6%) were treated and 29 cases (23.2%) were not treated. Univariate analysis showed that age, occupation, marital status and group intervention were the related factors affecting the prognosis of multi-drug resistant pulmonary tuberculosis, the difference was statistically significant. Multivariate regression analysis revealed that participation in group interventions (0 and 4: Waldx~2=13.333,P0.01,OR=4.315,95%CI=3.672~74.813) and gender (male and female: Waldx~2=5.248,P0.05,) OR=-0.146,95%CI=0.152~-0.864) is the main influencing factor of treatment effect in drug-resistant pulmonary tuberculosis patients. And the data showed that the more frequent patients participated in group intervention, the better their drug compliance was, and the more objective they could assess the severity of adverse reactions (x / 2 / 33.82, P 0.01 / 2 / 13.96, P 0.01 / 13.96, P < 0.01), and the higher the frequency of group intervention, the better their compliance with medication and their ability to assess the severity of adverse reactions more objectively. Conclusion in the course of treatment of MDR-TB patients, group intervention can improve the prognosis and cure rate of MDR-TB.
【作者单位】：云南省疾病预防控制中心结防所;北京协和医学院护理学院;
【基金】：FHI360(美国家庭健康国际) 世界卫生组织国际护士会
【分类号】：R473.5

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