酒精对驾驶员视网膜电图和视觉诱发电位的影响

发布时间：2018-04-12 23:41

  本文选题：视网膜电图 + 视觉诱发电位　； 参考：《重庆医科大学》2006年硕士论文

【摘要】： 目的:观察酒精对重庆地区驾驶员图形视网膜电图(PERG)、闪光视网膜电图(FERG)和图形视觉诱发电位(PVEP)的影响,分析酒精对驾驶员视功能的损害机制,从而为交通安全立法、预防交通事故提供科学依据。 方法:在重庆地区20~50岁年龄段中随机抽取30名驾驶员志愿者作为受试对象,男性23名,女性7名,平均年龄34±8.3岁。所有受试者经检查均为无酒精过敏、酒精依赖、眼病和重大疾病的健康者。以自身为对照,首先在饮酒前60min内对驾驶员进行PERG、FERG和PVEP检查,记录数据;然后按其自报酒量(既往饮酒量以酒精度56%白酒计算),并按照中国人的习惯同时进餐荤素混吃饮酒,饮酒过程为10min。30min后,抽取2ml静脉血标本,由5ml试管封装,0℃低温保存,24h内用顶空气相色谱法测BAC,并再次对饮酒后驾驶员进行PERG、FERG和PVEP检查,记录数据。 结果:(1) BAC20mg/100ml时, PVEP-P100、FERG-Pb和PERG-P50波潜时和振幅与饮酒前相比,均无显著性差异(P0.05)。(2)20mg/100ml≤BAC80mg/100ml时, PVEP-P100波和FERG-Pb波潜时均显著延长(P0.05);PVEP-P100波振幅有所降低,但与饮酒前无
[Abstract]:Objective: to observe the effects of alcohol on driver's visual function in Chongqing area, and to analyze the mechanism of alcohol's damage to driver's visual function, so as to legislate for traffic safety, and to observe the effects of alcohol on driver's visual function, such as PERGG, flash electroretinogram (ERG) and visual evoked potential (PVEP).Prevention of traffic accidents provides scientific basis.Methods: a total of 30 pilot volunteers were randomly selected from 20 to 50 years old in Chongqing, including 23 males and 7 females, with an average age of 34 卤8.3 years.All subjects were tested for non-alcoholic allergy, alcohol dependence, eye disease, and major diseases.As a control, the driver was checked by Perger and PVEP in 60min before drinking, and the data were recorded, and then according to their self-reported alcohol quantity (past alcohol consumption was calculated by alcohol content of 56% liquor), and the Chinese people's habit of eating meat and vegetables, drinking and drinking at the same time,After drinking with 10min.30min, the venous blood samples of 2ml were collected, and the 2ml was measured by headspace gas chromatography within 24 hours after 5ml encapsulated at 0 鈩，

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