中国南方汉族群体九个短片段长度Y-STR基因座的遗传多态性及其法医学应用

发布时间：2018-05-13 02:06

  本文选题：Y染色体 + 短串联重复序列　； 参考：《中华医学遗传学杂志》2006年04期

【摘要】：目的研究中国南方汉族群体中,扩增产物片段长度在180bp以下的9个Y染色体的短串联重复(Y-shorttandemrepeat,Y-STR)基因座的遗传多态性,并用于法医学鉴定。方法采用PCR复合扩增和基因测序仪荧光检测方法,检测213个无关男性个体,调查南方汉族的9个Y-STR基因座的等位基因频率和单倍型频率,并对84对真父子和36对非父子的亲子鉴定样本进行检测。结果213个无关男性个体中,DYS426基因座检出3个等位基因,DYS393、DYS460、DYS391和DYS389Ⅰ基因座均检出了5个等位基因,DYS456基因座检出6个等位基因,H4和DYS388基因座检出7个等位基因,DYS
[Abstract]:Objective to study the genetic polymorphism of the short tandem repeat (STR) loci of 9 Y chromosomes with amplified product fragments below 180bp in the Han population of southern China, and to identify them in forensic medicine. Methods the allelic and haplotype frequencies of 9 Y-STR loci were investigated in 213 unrelated male individuals by PCR multiplex amplification and gene sequencing. The paternity test samples of 84 true parents and 36 non-paternal parents were tested. Results in 213 unrelated male individuals, 3 alleles were detected in DYS426 locus and 5 alleles were detected in DYS460DYS391 and DYS389 鈪，

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