类Salen化合物的制备、单晶结构及分子识别研究

发布时间：2018-05-04 19:38

本文选题：类Salen配体 + 单晶结构　；参考：《河北工业大学》2015年硕士论文

【摘要】：类Salen配体以及配合物由于自身具有特殊的空间立体效应,有些甚至具有荧光特性,因此在催化、识别领域有重大意义。本论文工作内容如下:以2,4-二叔丁基苯酚、3,5-二叔丁基水杨醛等为主要原料合成了两种类Salen配体,通过IR、1H NMR、13C NMR、元素分析等手段对其进行了表征。将得到的两种类Salen配体通过溶剂挥发法得到了两种化合物的晶体,利用X射线单晶衍射仪对其结构进行解析,对两种结构进行对比。通过紫外可见光谱、荧光光谱考察了类Salen配体与金属离子(Li+、Na+、K+、Cd2+、Cs2+、Co2+、Cu2+、Hg2+、Mn2+、Ni2+、Zn2+)的识别与配位性能,得出类Salen配体是同时具有高选择性和高灵敏度的Zn2+荧光传感器。本文通过紫外可见光谱测试了类Salen配合物与含氮小分子(咪唑、N-甲基咪唑、吡啶以及2,6-而甲基吡啶)、小牛胸腺DNA的相互作用,得出结论,类Salen配合物能够很明显地识别含氮小分子,也可以插入到DNA的双螺旋结构中,且与DNA分子结合使DNA结构破坏。
[Abstract]:Salen like ligands and complexes have great significance in the field of catalysis and recognition because of their special spatial stereoscopic effects and even fluorescence properties. The main contents of this thesis are as follows: two kinds of Salen ligands were synthesized from 2H 4- di-tert Ding Ji phenol 3 + 5-di-tert Ding Ji salicylaldehyde and characterized by IR 1H NMRN 13C NMRs and elemental analysis. The crystals of two kinds of Salen ligands were obtained by solvent volatilization method. The structures of the two compounds were analyzed by X-ray single crystal diffractometer and the two structures were compared. The identification and coordination properties of Salen like ligands and metal ions Li Li Na Na, K, K, CD 2, Cs2 / Co 2, Cu 2, Hg 2, mn 2 and Ni 2 + Zn 2) were investigated by UV-Vis spectra. It was concluded that Salen like ligands are Zn2 fluorescence sensors with high selectivity and high sensitivity at the same time. The interaction of Salen complexes with small nitrogen-containing molecules (imidazolium N-methylimidazole, pyridine, 2-dimethylpyridine, calf thymus DNA) was investigated by UV-Vis spectra. Salen like complexes can clearly recognize small nitrogen-containing molecules, can also be inserted into the double helix structure of DNA, and combine with DNA molecules to destroy the DNA structure.
【学位授予单位】：河北工业大学
【学位级别】：硕士
【学位授予年份】：2015
【分类号】：O641.4

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