超声造影、血流动力学参数、微血管密度在前列腺癌与慢性前列腺炎中的诊断价值

发布时间：2017-12-31 09:05

  本文关键词：超声造影、血流动力学参数、微血管密度在前列腺癌与慢性前列腺炎中的诊断价值　出处：《广西医科大学》2017年硕士论文　论文类型：学位论文

  更多相关文章： 血流动力学参数 微血管密度 超声造影参数 前列腺癌 Gleason评分

【摘要】：目的:评价微血管密度(microvessel density,MVD)、超声造影参数、血流动力学参数在前列腺癌(prostatic cancer,PCa)与慢性前列腺炎(chronic prostatitis,CP)中的差异及相关性,为PCa与CP的诊断及鉴别诊断、PCa的预后提供帮助。方法:对广西医科大学第一附属医院2014-2015年泌尿外科收治入选的前列腺病患68例行前列腺经直肠超声(Transrectal Ultrasonography,TRUS),获取血流动力学参数;前列腺经直肠超声造影(contrast enhanced transrectal ultrasound,CETRUS),获取造影参数;超声引导下穿刺活检或手术明确病理类型及格里森(Gleason)评分;进行免疫组化MVD的测定。比较PCa组与CP组、PCa中Gleason评分≤3+4组与Gleason评分≥4+3组的血流动力学、MVD、超声造影参数的差异;研究PCa中MVD与血流动力学参数、超声造影参数的相关性。结果:病理证实前列腺癌患者44例,CP患者24例。PCa组与CP组中的收缩期峰值血流速度(Velocity of flow in systolic,Vs)、阻力指数(Resistance Index,RI)、初始强度(Basic intensity,B)、曲线下面积(Area under the curve,AUC)、峰值强度(Peak Intensity,PI)、MVD差异均有统计学意义(P0.05);PCa中Gleason评分≥4+3组28例,Gleason评分≤3+4组16例,两组间Vs、RI、MVD差异有统计学意义(P0.05);PCa中Vs、RI、AUC与MVD具有正相关(P0.05),r分别为0.578、0.688、0.737。结论:血流动力学、超声造影参数、微血管密度为PCa与CP的诊断与鉴别诊断提供帮助;前列腺癌中超声造影、血流动力学参数可较好的反映微血管密度;血流动力学参数、微血管密度对PCa患者预后的判断有一定价值。
[Abstract]:Objective: to evaluate the microvessel density (MVDV) of microvessel density (MVD), and to evaluate the parameters of contrast-enhanced ultrasound (CEUs). Hemodynamic parameters were found in prostatic cancer PCA and chronic prostatitis prostatitis. The difference and correlation between PCa and CP were the diagnosis and differential diagnosis of PCa and CP. The prognosis of PCa. Methods: 68 patients admitted to urology department in the first affiliated Hospital of Guangxi Medical University from 2014 to 2015 underwent transrectal ultrasound (TUS). Transrectal Ultrasonography. Trust to obtain hemodynamic parameters; Contrast enhanced transrectal ultrasound trust was used to obtain the parameters of prostate contrast transrectal ultrasound. Ultrasound-guided biopsy or surgery was performed to determine the pathological type and Gleason score. To compare the hemodynamics of Gleason score 鈮，

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