天山区维吾尔族甲状腺结节患病率及其影响因素

发布时间：2018-02-07 16:09

  本文关键词： 甲状腺结节 患病率 影响因素　出处：《新疆医科大学》2017年硕士论文　论文类型：学位论文

【摘要】：目的:探讨新疆乌鲁木齐市天山区维吾尔族甲状腺结节的患病率,并探究其影响因素。方法:应用整群随机抽样方式,在2015年9-12月期间内选取20~80岁的乌鲁木齐市天山区居民为研究对象。对研究对象分发流行病学调查表,调查基本情况、甲状腺病史,家族史,饮食习惯和生活习惯等方面的情况,检查并测量身高、体重、血压、腰围,计算得出体重指数(BMI);收集空腹静脉血及中段晨尿,测定血糖、糖化血红蛋白、血脂、尿酸、尿碘等;应用甲状腺超声来确诊甲状腺结节。使用单因素及多因素Logistic回归分析来得出甲状腺结节的影响因素。结果:其中1500例调查对象中1268人完成调查,实际调查率为84.53%。天山区维吾尔族总人群中患病率为27.21%(345/1268),男性为20.49%(118/576),女性为32.80%(227/692)。女性高于男性,差异有统计学意义(X2=24.080,P0.01)。18~29、30~39、40~49、50~59、60~80岁甲状腺结节患病率分别为14.55%(55/378)、16.07%(45/280)、29.93%(88/294)、45.15%(93/206)、58.18%(64/110),甲状腺结节患病率随着年龄的增长,随之升高(X趋势2=126.591,P0.01)。单因素Logistic回归分析结果显示:性别、年龄、吸烟史、轻度进食盐习惯、BMI为24.0~27.9kg/m2和≥28.0 kg/m2、腰围、空腹血糖(FPG)、口服葡萄糖耐量试验(OGTT)-2 h血糖、糖化血红蛋白、收缩压、舒张压、低密度脂蛋白、甘油三酯、总胆固醇、促甲状腺激素(TSH)4.20 mU/L、甲状腺过氧化物酶抗体(TPOAb)、甲状腺球蛋白抗体(TGAb)、糖尿病、高血压、血脂异常、甲状腺功能减退、甲状腺肿是甲状腺结节的影响因素(P0.05)。多因素Logistic回归分析结果显示:年龄、性别和收缩压为甲状腺结节的独立危险因素(P0.05)。结论:新疆乌鲁木齐市天山区维吾尔族甲状腺结节患病率较高,影响因素较多,应做到早期预防、诊断及治疗。
[Abstract]:Objective: to investigate the prevalence of thyroid nodule in Uygur nationality in Tianshan District of Urumqi, Xinjiang, and to explore its influencing factors. Methods: cluster random sampling was used. During the period from September to December in 2015, the residents of Tianshan District, aged 20 or 80 years old, were selected as the subjects of the study. The epidemiological questionnaire was distributed to the subjects to investigate the basic situation, the history of thyroid diseases, family history, diet habits and habits of life and so on. Height, weight, blood pressure, waist circumference were measured, body mass index (BMI) was calculated, fasting venous blood and midmorning urine were collected, blood glucose, glycosylated hemoglobin, blood lipids, uric acid, urine iodine were measured. Univariate and multivariate Logistic regression analysis was used to determine the influencing factors of thyroid nodules. The actual rate of investigation is 84.53.The prevalence rate of thyroid nodules in the Uygur population in Tianshan District is 27.2145% 1268%, 20.499,118,576% for men, 32.80% 2227% 692% for women. The difference is statistically significant. The difference is statistically significant. The results of univariate Logistic regression analysis showed that: sex, age, smoking history, mild salt intake habit were 24.0 ~ 27.9 kg / m ~ 2 and 鈮，

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