三种局部药物对预防口腔种植术后感染的疗效评价

发布时间：2018-03-21 07:18

本文选题：口腔种植　切入点：预防感染　出处：《新疆医科大学》2017年硕士论文　论文类型：学位论文

【摘要】：目的:评价种植术后分别给予复方氯已定含漱液、西吡氯铵含片、西帕依固龈液等三种措施预防种植体术后感染的临床疗效,为未来的临床工作提供参考依据。方法:选择2015年至2016年在新疆医科大学第二附属医院口腔科行种植手术的患者为研究对象,根据排除纳入标准选取60例患者,采用随机数字表法分为对照组与实验A、B、C共四组,每组15例。对照组在种植手术后给予生理盐水漱口一周、复方氯已定实验A组在种植手术后用复方氯已定含漱液漱口一周、西帕依固龈液实验B组在种植手术后用西帕依固龈液漱口一周、西吡氯铵含片实验C组种植手术后给予西吡氯铵含片一周。通过患者术后第二天对疼痛感的评价、术后一周伤口愈合情况、术后一周牙周指数(改良菌斑指数,改良牙龈指数,改良龈沟出血指数)检查、龈沟细菌培养计数等指标,术后三个月通过X线片与临床指征观察种植体初期稳定性,对比评价对照组与三组实验药物的疗效。结果:四组间年龄、性别、种植部位等基本信息均衡,疼痛度、伤口愈合情况、牙龈指数、牙龈出血指数、菌斑指数等指标,细菌培养计数结果差异均有统计学意义(P0.05)。结论:复方氯已定含漱液、西吡氯铵含片、西帕依固龈液等三种局部抗菌药物疗效可靠,可以有效预防种植体植入后的早期感染。
[Abstract]:Objective: to evaluate the clinical efficacy of compound chlorhexidine gargle, cepiramide buccal tablet and sipanil gingival fluid in preventing postoperative infection after implant implantation. Methods: from 2015 to 2016, 60 patients undergoing implant surgery in the Department of Stomatology, second affiliated Hospital of Xinjiang Medical University were selected according to the exclusion criteria. The control group was divided into four groups with 15 cases in each group. The control group was gargled with normal saline for one week, and the compound chlorhexidine group A was gargled with compound chlorhexidine gargle for one week after implantation. After implantation, group B was gargled with cipramine gingival fluid for one week, and group C was given cipiramine buccal tablet for one week after implantation. The pain was evaluated on the second day after implantation. One week after operation, wound healing, periodontal index (modified plaque index, modified gingival index, modified gingival sulcus bleeding index), gingival sulcus bacterial culture count, etc. Three months after operation, the initial stability of implant was observed by X-ray film and clinical indication, and the curative effect of experimental drugs in control group and three groups was compared. Results: the basic information of age, sex, site of implantation was balanced and pain degree was observed among the four groups. There were significant differences in wound healing, gingival index, gingival bleeding index, plaque index and bacterial culture count. Three local antimicrobial agents such as Cipayl gingival fluid are effective in preventing early infection after implant implantation.
【学位授予单位】：新疆医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R783.6

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