探讨子宫动脉栓塞术治疗子宫肌瘤的临床效果

发布时间：2018-04-27 20:14

本文选题：子宫肌瘤 + 介入治疗　；参考：《新疆医科大学》2017年硕士论文

【摘要】：目的:探讨子宫动脉栓塞术(uterine artery embolization,UAE)治疗子宫肌瘤的临床效果及其对卵巢功能的影响。方法:收集2014年9月至2016年1月在我院就诊的自愿接受子宫动脉栓塞治疗的子宫肌瘤患者50例,均在月经干净后3~7天内采用Seldinger技术进行股动脉穿刺,双侧子宫动脉经动脉造影证实后实施子宫动脉栓塞治疗。结果:50例患者均成功实施了子宫动脉栓塞术,部分患者于术后1~3d均出现了不同程度地下腹痛、发热、少量阴道流血、排液等症状,持续4~6d后大多数可好转,50例患者均未出现严重并发症。50例患者于术后3月、6月、12月分别行B超复查子宫与瘤体体积,术后随访患者血红蛋白、卵泡刺激素(Follicle-stimulating hormone,FSH)及黄体生成素(Luteinizing homone,LH)水平,多个时间点的重复测量资料首先采用重复测量方差分析,两两比较采用配对t检验,结果显示子宫与瘤体体积均缩小,随着UAE时间延长,子宫及瘤体体积均进行性缩小,差异有统计学意义(P0.01);UAE术后3月、6月、12月血红蛋白水平均较术前有了不同程度的提高,差异有统计学意义(P0.01);UAE术前、术后3个月、6个月、12个月LH、FSH水平均无明显变化,UAE术前术后差异无统计学意义(P0.05)。结论:采用子宫动脉栓塞术治疗子宫肌瘤方法简单、创伤小、恢复快,并且术后对卵巢功能影响较小,是治疗子宫肌瘤的一种安全有效的方法,临床上有广泛的应用前景。
[Abstract]:Objective: to investigate the clinical effect of uterine artery embolization (artery) in the treatment of uterine leiomyoma and its effect on ovarian function. Methods: from September 2014 to January 2016, 50 patients with uterine leiomyoma who voluntarily received uterine artery embolization were collected. The femoral artery puncture was performed by Seldinger technique within 3 days after menstruation. Uterine artery embolization was performed after bilateral uterine artery was confirmed by arteriography. Results uterine artery embolization was performed successfully in all 50 patients. Some of the patients had symptoms of lower abdominal pain, fever, vaginal bleeding and drainage at 1 and 3 days after operation. After 4 ~ 6 days, the majority of 50 patients without serious complications were examined by B-ultrasound in 3 months, 6 months and 12 months after operation. Hemoglobin was followed up after operation. The levels of Follicle-stimulating hormone (FSHH) and luteinizing homoneone (LH) in follicle stimulating hormone (FSH) and luteinizing homoneone (LH) were measured. The repeated measurement data at several time points were first analyzed by repeated measurement variance analysis, and paired t test was used to compare the results. The results showed that the volume of uterus and tumor was reduced. With the prolongation of UAE time, the volume of uterus and tumor gradually decreased, and the difference was statistically significant (P 0.01). The hemoglobin levels in 3 months, 6 months and 12 months after operation were higher than those before operation, and the difference was statistically significant. There was no significant change in the level of LHG FSH at 3 months, 6 months and 12 months after UAE. There was no significant difference between the two groups before and after UAE (P 0.05). Conclusion: uterine artery embolization is a safe and effective method for the treatment of uterine leiomyoma.
【学位授予单位】：新疆医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R737.33

【参考文献】