腹腔镜与开腹结肠癌CME手术临床疗效比较研究

发布时间：2018-04-29 20:43

  本文选题：腹腔镜 + 结肠癌　； 参考：《青海大学》2017年硕士论文

【摘要】：目的:对比腹腔镜CME手术与开腹CME手术治疗结肠癌的疗效。方法:分析青大附院肿瘤外科在2015年3月到2016年5月之间完成的腹腔镜CME及开腹CME手术共47例,通过分析两组的手术时间、术中出血量、术后离床时间、术后首次排气时间、术后进流食时间、术后在院天数、总费用、清扫而获得的淋巴结数目、病理标本肿瘤大小、远,近切缘距离,术后并发症发生率临床指标而得出结论。结果:通过对比,两组患者的一般资料如年龄,性别,体重指数(BMI),肿瘤所处位置及术前肿瘤的临床分期未见明显差异。腹腔镜组与开腹组在手术失血量(79.3±8.3ml,123.9±10.1ml,P0.05),术后下床时间(21.7±6.6h,25.8±6.5h,P0.05),术后排气时间(70.7±6.8h,80.2±6.1h,P0.05),术后住院天数(10.9±3.9d,14.5±3.3d,P0.05)方面的差异有统计学意义,而两者在手术时间(176.9±16.8min,167.1±16.6min,P0.05),清扫淋巴结数目(18.5±4.5,19.9±4.1,P0.05)、近切缘距离(14.7±3.5,13.5±5.2cm,p0.05)、远切缘距离(17.5±8.0,20.7±8.6cm,p0.05)、肿瘤大小(5.8±1.2,5.1±1.5cm,p0.05)、术后并发症发生率(7.4%,20%,p0.05)、Clavien-Dindo分级为Ⅰ,Ⅱ级患者所占比例(7.4%,20%,p0.05)总费用(6.3±1.1万元,6.2±1.6万元,P0.05)方面的差异无统计学意义。结论:腹腔镜CME手术具有出血量少,康复快的优点,同时在安全性及肿瘤根治的方面能达到和开腹CME手术相当的效果。
[Abstract]:Objective: to compare the efficacy of laparoscopic CME operation and open CME operation in the treatment of colon cancer. Methods: a total of 47 cases of laparoscopic CME and open CME were performed in tumor surgery of Qingda affiliated Hospital from March 2015 to May 2016. The time of operation, intraoperative bleeding, postoperative time out of bed and the time of first postoperative exhaust were analyzed in the two groups. The time of feeding, the days in hospital, the total cost, the number of lymph nodes obtained by dissection, the size, distance and distance of tumor, and the incidence of postoperative complications were analyzed. Results: there was no significant difference in general data such as age, sex, body mass index (BMI), tumor location and preoperative clinical stage between the two groups. There were significant differences in blood loss (79.3 卤8.3 ml), postoperative time (21.7 卤6.6 h), postoperative time (25.8 卤6.5 h, P 0.05), postoperative exhaust time (70.7 卤6.8 h, 80.2 卤6.1 h, P 0.05), postoperative hospitalization days (10.9 卤3.9dU, 14.5 卤3.3dg, P 0.05) between the laparoscopic group and the laparotomy group, and there was significant difference between the laparoscopic group and the laparotomy group in terms of postoperative blood loss (79.3 卤8.3ml), postoperative time of getting out of bed (21.7 卤6.6hs, 25.8 卤6.5hP0.05), postoperative days of hospitalization (10.9 卤3.9dU, 14.5 卤3.3dg). The operative time was 176.9 卤16.8min, 167.1 卤16.6 min, P0.05, the number of lymph nodes dissected, 14.7 卤3.5cm. 13.5 卤5.2cm, 17.5 卤8.020.7 卤8.6cmp0.05, and the size of tumor 5.8 卤1.2cm. p0.05. the incidence of postoperative complications was 7.420p0.05p0.05. the incidence of postoperative complications was 7.420p0.05p0.05a, and the classification of Clavien-Dindo was 鈪，

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