胃癌耳穴特异性变化的临床研究

发布时间：2018-05-01 10:04

  本文选题：胃癌 + 耳穴　； 参考：《大连医科大学》2017年硕士论文

【摘要】：目的:通过耳穴望诊、触诊及电测三种方法对临床胃癌患者双耳耳廓相关耳穴特异性变化进行观察研究,进行耳穴诊断胃癌相关性、相符率的比较,为进一步研究通过耳穴辅助诊断胃癌提供参考。为临床早期发现胃癌提供简便、安全、经济、可靠的初步筛查诊断方法。方法:根据既往研究经验与耳穴诊断理论选取双耳耳穴口、食管、贲门、胃、十二指肠、小肠、大肠、肝、脾、皮质下、肾上腺、肿瘤特异区(M1、M2、M3),共14个穴位。分别采用耳穴望诊法、触诊法以及电测法,对39例胃癌术前患者,35例慢性萎缩性胃炎患者以及36例健康者耳廓进行相关穴位特异性变化的临床观察与检测。记录相关耳穴颜色和形态的变化,并用相机采集照片,然后用Adobe photoshopCS6对照片进行处理后,进行色差分析。分别用XDM-III型耳穴探测仪和CLRH-A型耳穴探测器共同检测胃癌患者、慢性萎缩性胃炎患者及健康人双耳耳穴的低电阻阳性反应点,并加以记录。然后用SPSS22.0进行统计分析,分别比较胃癌患者、慢性萎缩性胃炎患者以及健康人之间耳廓的相关耳穴差异性。结果:1.胃癌组与健康人组比较:在颜色、形态以及电测上两组均存在着明显差异性。(1)颜色上,尤其在耳穴胃区和肿瘤特异区II(M2)改变最为明显,胃癌组耳穴胃区与健康组相比颜色晦暗无光,部分患者出现褐色斑点,肿瘤特异区II出现暗灰色或棕褐色色斑,胃区与肿瘤特异区改变与健康组比较均存在统计学差异(P0.01,P0.01),经色差分析比较,存在的统计学差异(P0.01,P0.01)。(2)形态上,胃癌组大多数患者胃区出现结节改变,与健康组相比差异具有显著统计学意义(P0.01)。(3)电测上,胃癌组贲门、胃、十二指肠、脾、皮质下、肿瘤特异区(M1、M3)出现大量阳性反应,与健康组相比差异具有显著统计学意义(P0.01)。2.胃癌组与慢性萎缩性胃炎组比较:(1)颜色上,胃癌组与慢性萎缩性胃炎组相比出现较多例数胃区呈棕褐色或暗灰色改变以及肿瘤特异区II(M2)呈暗灰色或棕褐色色斑改变,差异均有统计学意义(P0.05,P0.05),通过色差分析比较,均具有统计学差异(P0.05,P0.05)。(2)形态上,胃癌组胃区出现结节改变较慢性萎缩性胃炎患者组明显增多,有统计学差异(P0.05)。(3)电测上,胃癌组耳穴胃、皮质下较慢性萎缩性胃炎组出现低电阻阳性反应多,差异具有统计学意义(P0.05)。肿瘤特异区(M1、M3)出现大量阳性反应,与慢性萎缩性胃炎组相比差异具有显著统计学意义(P0.01)。3.慢性萎缩性胃炎组与健康组比较:(1)颜色上,在胃区和肿瘤特异区II(M2)颜色改变上无统计学差异。但通过色差分析,健康组与萎缩性胃炎组在胃区和肿瘤特异区II(M2)存在色差差异(P0.05,P0.05)。(2)形态上,部分慢性萎缩性胃炎患者出现胃区结节改变,与健康组组相比差异具有统计学意义(P0.01)。(3)电测上,胃癌组与健康组比较在贲门、胃、十二指肠、脾、皮质下均具有显著统计学差异(P0.01)。肿瘤特异区(M1、M3)则无统计学意义。结论:胃癌患者与健康人和慢性萎缩性胃炎患者比较,在耳廓相关耳穴的颜色、形态以及电测上均存在着明显差异。充分说明耳穴诊断法对胃癌具有一定的临床辅助诊断价值,在胃癌的普查中值得进一步的探究与推广。
[Abstract]:Objective: To observe and study the auricular specific changes of the auricular auricle in the clinical gastric cancer patients by three methods of auricular acupoint inspection, palpation and electrical measurement, and the correlation of the diagnosis of gastric cancer by ear acupoint diagnosis, and the comparison of the coincidence rate for the further study of the diagnosis of gastric cancer by ear acupoint assistance. It provides a simple, safe and economical method for the early detection of gastric cancer. A reliable preliminary screening diagnostic method. Methods: according to the previous research experience and ear point diagnosis theory, we selected the auricular acupoint mouth, the esophagus, the cardia, the stomach, the duodenum, the small intestine, the large intestine, the liver, the spleen, the cortex, the adrenal gland, the tumor specific area (M1, M2, M3), with 14 points, respectively, with the auricular examination, palpation and electrical measurement, respectively, for the preoperative suffering of 39 cases of gastric cancer. In 35 cases of chronic atrophic gastritis and 36 healthy subjects, the specific changes in the auricle of the auricle were observed and detected. The changes in the color and shape of the auricular points were recorded, and the photographs were collected with a camera, and then the color difference was analyzed with Adobe photoshopCS6. The XDM-III type auricular probe and CLR were used respectively. H-A type auricular detector was used to detect and record the low resistance positive reaction point of gastric cancer patients, chronic atrophic gastritis and healthy people, and then recorded by SPSS22.0, and then compared the auricular points of gastric cancer patients, chronic atrophic gastritis and healthy people. Results: 1. gastric cancer group. Compared with the healthy group, there were obvious differences between the two groups in color, shape and electrical test. (1) the color, especially in the auricular area and the tumor specific area II (M2) was most obvious, the gastric area of the gastric cancer group was dark and dark compared with the health group, some patients appeared brown spots, and the tumor specific area II appeared dark grey or brown. There were significant differences in color spots, gastric area and tumor specific area changes (P0.01, P0.01), and the statistical difference (P0.01, P0.01) compared with the color difference analysis (P0.01, P0.01). (2) in the form of gastric cancer, most of the patients had nodular changes in gastric area, and there were significant statistical significance (P0.01). (3) gastric carcinoma group cardia cardia. A large number of positive reactions were found in the portal, stomach, duodenum, spleen, subcortex and tumor specific area (M1, M3). Compared with the healthy group, the difference was significant (P0.01) compared with the chronic atrophic gastritis group (P0.01): (1) the color, gastric cancer group and chronic atrophic gastritis group had many cases of brown or dark grey change in the gastric region. And the tumor specific area II (M2) showed a dark grey or brown color spot change, the difference was statistically significant (P0.05, P0.05), by color difference analysis, all had statistical differences (P0.05, P0.05). (2) the morphological changes of gastric cancer group were significantly increased in gastric cancer group than chronic atrophic gastritis patients (P0.05). (3) electric test, stomach The positive reaction of low resistance in the cancer group was more than that in the chronic atrophic gastritis group. The difference was statistically significant (P0.05). The tumor specific area (M1, M3) had a large number of positive reactions. Compared with the chronic atrophic gastritis group, the difference had significant statistical significance (P0.01).3. chronic atrophic gastritis group was compared with the healthy group: (1) color, There was no statistical difference in the color change of II (M2) in the stomach and tumor specific areas. But by color difference analysis, there was a difference in color difference between the healthy group and the atrophic gastritis group in the gastric region and the tumor specific area II (M2) (P0.05, P0.05). (2) part of the chronic atrophic gastritis patients showed the change of the gastric nodule, and the difference was statistically significant compared with the healthy group. Significance (P0.01). (3) electrical measurement, the gastric cancer group and the health group compared to the cardia, stomach, duodenum, spleen, cortex all have significant statistical difference (P0.01). The tumor specific area (M1, M3) has no statistical significance. Conclusion: gastric cancer patients and healthy people and chronic atrophic gastritis patients, in the auricle related auricular color, morphology and electrical measurement are all There are obvious differences. It is fully explained that the auricular point diagnosis has certain clinical auxiliary diagnostic value for gastric cancer, and it is worth further exploring and popularizing in the general survey of gastric cancer.

【学位授予单位】：大连医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R735.2
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本文编号：1828848