基于数据挖掘的朱佳教授运用虫类药治疗慢性咳嗽的医案研究

发布时间：2018-05-07 18:40

本文选题：慢性咳嗽 + 朱佳　；参考：《南京中医药大学》2017年硕士论文

【摘要】：研究目的:本文通过对朱佳教授配伍虫类药治疗慢性咳嗽的临床医案进行数据挖掘,系统总结和归纳朱佳教授治疗慢性咳嗽的总体思想和灵活运用虫类药配伍的特色,为慢性咳嗽的中医诊疗提供思路和方法。研究方法:收集、整理朱佳教授2011年1月至2016年11月临床配伍虫类药诊治慢性咳嗽的医案,共涉及364例病例,累计386诊次。采用频数分析、关联规则分析的数据挖掘方法,结合朱佳教授的临证经验对挖掘结果进行分析、归纳和总结。结果:数据挖掘频数分析结果显示386诊次中男性105例108诊次,女性259例278次。慢性咳嗽的主要临床表现为咳嗽、咽喉痒、痰白、阵咳、痰少、干咳,在所有诊次中分别占 91.19%、48.96%、34.46%、31.87%、29.27%、27.20%;病机多为风邪恋肺、风痰阻肺、肺脾两虚等,在所有诊次中分别占36.27%、24.61%、11.14%;关联规则分析结果显示虫类药(蝉蜕、僵蚕、蜈蚣、全蝎、地龙)与临床症状、舌象、脉象、病机外关联都存在着较强的关联性。结论:通过研究发现,慢性咳嗽以风痰阻肺、风邪恋肺为主要病机,久咳不愈常出现肺脾两虚等虚证,属于本虚标实。虫类药(蝉蜕、僵蚕、蜈蚣、全蝎、地龙)既可祛外风,又善息内风,还可化痰散结,主要应用在咽喉痒、阵咳、干咳、痰少、痰白、夜间咳甚,舌淡红或红,苔薄或薄黄,脉细弦或细滑,辨证为风邪恋肺证、风痰阻肺证的慢性咳嗽患者。
[Abstract]:Objective: through the data mining of professor Zhu Jia's clinical records of treating chronic cough, the author summarized and summarized the general thought of professor Zhu Jia's treatment of chronic cough and the characteristics of flexible application of insect medicine compatibility To provide ideas and methods for the diagnosis and treatment of chronic cough. Methods: a total of 364 cases involving 364 cases of chronic cough were collected and sorted out by Professor Zhu Jia from January 2011 to November 2016. The data mining method based on frequency analysis and association rule analysis is used to analyze and summarize the mining results combined with Professor Zhu Jia's clinical experience. Results: the data mining frequency analysis showed that 105 cases (108 times) were male and 259 cases (278 times) were women. The main clinical manifestations of chronic cough are cough, itching of throat, phlegm white, phlegm, dry cough, which account for 91.199,48.96 and 34.8729.277.20 respectively in all visits. The pathogenesis of chronic cough is mostly wind evil love of lung, wind phlegm blocking lung, deficiency of lung and spleen, etc. The results of association rule analysis showed that insect drugs (cicada slough, Bombyx bassiana, centipede, scorpion, Geosaurus) had strong correlation with clinical symptoms, tongue, pulse and pathogenesis. Conclusion: the main pathogenesis of chronic cough is wind phlegm blocking lung and wind evil falling in love with lung. Deficiency syndrome such as deficiency of lung and spleen and deficiency of lung and spleen are often found in chronic cough. Insect medicine (cicada slough, silkworm, centipede, scorpion, earth dragon) can not only quell the outside wind, but also soothe the internal wind, but also can dissipate phlegm and disperse the knot. It is mainly used in throat itching, coughing, dry cough, phlegm less, phlegm white, night cough very, tongue pale red or red, thin or thin yellow moss. Pulse fine string or fine smooth, syndrome differentiation is wind evil love lung syndrome, wind phlegm block lung chronic cough patients.
【学位授予单位】：南京中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R249;R256.11

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