椎动脉夹层动脉瘤的血管内治疗疗效分析

发布时间：2018-05-12 06:00

本文选题：椎动脉夹层动脉瘤 + 血管内治疗　；参考：《新疆医科大学》2017年硕士论文

【摘要】：目的:分析椎动脉夹层动脉瘤(vertebral artery dissecting aneurysm,VADA)的发病特点根据血管结构的血管内治疗方案及其有效性、安全性。方法:回顾性分析新疆医科大学第一附属医院神经外科2012年1月至2016年12月血管内治疗椎动脉夹层动脉瘤32例患者的临床资料,主要包括民族,性别,年龄,既往史(高血压病史,糖尿病史,吸烟史,饮酒史),临床症状(头痛,头晕,恶心,呕吐,意识障碍),入院时Hunt-Hess分级,改良Fisher分级、动脉瘤部位,入院和出院时mRS预后评分,术后及造影复查后动脉瘤栓塞程度,对这些资料进行统计学分析总结。结果:32例椎动脉夹层动脉瘤患者中,男20例,女12例,平均年龄为48.7±10.2岁,有21例年龄在30~50岁之间。全部男女性患者年龄均符合正态分布。出院时预后良好的(mRS评分在0~2分)占总数的81.25%,入院和出院时mRS评分有显著差异(?2=4.65;P=0.031)。结论:椎动脉夹层动脉瘤30-50岁发病率较高,而且女性发病率明显高于男性。椎动脉夹层动脉瘤根据血管结构行血管内治疗是安全、有效、并发症较少的治疗方案,患者预后主要取决于患者术前状况。
[Abstract]:Objective: to analyze the pathogenetic characteristics of vertebral artery dissecting aneurysm vertebral artery dissecting aneurysmma VADAA according to the intravascular treatment of vascular structure and its efficacy and safety. Methods: the clinical data of 32 patients with vertebral dissecting aneurysm treated by endovascular treatment in neurosurgery Department of the first affiliated Hospital of Xinjiang Medical University from January 2012 to December 2016 were retrospectively analyzed. Previous history (history of hypertension, diabetes, smoking, alcohol consumption), clinical symptoms (headache, dizziness, nausea, vomiting, disturbance of consciousness, Hunt-Hess grade at admission, modified Fisher grade, aneurysm site, mRS prognosis score on admission and discharge), clinical symptoms (headache, dizziness, nausea, vomiting, disturbance of consciousness). The degree of aneurysm embolization after operation and contrast examination were analyzed and summarized statistically. Results among 32 cases of vertebral dissecting aneurysm, 20 cases were male and 12 cases were female, the average age was 48.7 卤10.2 years, 21 cases were between 30 and 50 years old. All the male and female patients were in accordance with the normal distribution of age. The mRS scores of patients with good prognosis at discharge were 0 ~ 2), which accounted for 81.25% of the total. There was a significant difference in mRS scores between admission and discharge. Conclusion: the incidence of vertebral dissecting aneurysm in 30-50 years old is higher, and the incidence of female is higher than that of male. Endovascular treatment of vertebral artery dissecting aneurysm according to its vascular structure is a safe, effective and less complicated treatment. The prognosis of the patients mainly depends on the preoperative condition of the patients.
【学位授予单位】：新疆医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R743

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