《普济方》中葶苈子的配伍应用分析与研究

发布时间：2018-05-25 10:31

本文选题：普济方 + 葶苈子　；参考：《黑龙江中医药大学》2017年硕士论文

【摘要】：目的:论文旨在通过搜集文献和统计分析相结合的方法,对《普济方》中含葶苈子的方剂进行梳理,归纳总结《普济方》中葶苈子的配伍特点及中医古籍文献中对葶苈子相关的本草文献进行总结分析,并为临床上对葶苈子的配伍应用和新药的研发提供更广阔的思路,且为今后葶苈子的配伍应用的研究工作奠定一定的文献基础。方法:运用文献学和统计学的研究方法,《普济方》收录的方剂有61739首,其中含有葶苈子的方剂共有654首,占全书方剂总数的1.06%,和历代本草文献为依据,首次对其进行搜集、整理,筛选出含有葶苈子的方剂并建立方剂数据库,利用中医传承辅助平台(V2.5)统计软件对数据库进行频次分析、聚类分析、关联法分析等数据挖掘分析,最终对所得结果进行分析讨论。结论:通过对收集资料的研究分析,葶苈子的配伍的常见药物分类为泻下药、化痰止咳平喘药、补虚药、利水渗湿药等;治疗的常见疾病有水肿、喘证、咳嗽、鼓胀、痰饮、肺痈、肺胀、便秘、黄疸、积聚等。本文得出的结论是葶苈子配伍治疗水肿、喘证、咳嗽、鼓胀、痰饮等五种常见疾病,通过分析得其代表方剂,葶苈子治疗水肿的核心药物组合为"葶苈子-防己-郁李仁-茯苓-陈皮",代表方剂为葶苈丸。证型为湿热壅盛证,其配伍特点为通利三焦,气行则水行。葶苈子治疗喘证的核心药物组合为"葶苈子-杏仁-桑白皮-陈皮-甘草",代表方剂为郁李仁丸。证型为痰浊阻肺证,其配伍特点为使宣降得复,水湿运化致喘得以平。葶苈子治疗咳嗽的两组核心药物组合为"葶苈子-杏仁-桑白皮-陈皮-甘草"和"葶苈子-人参-乌梅-罂粟壳",代表方剂为陈橘皮散、宁神散。证型为痰湿蕴肺证和寒湿袭肺证,其配伍特点为一宣一散,使邪有出路和敛肺而不伤正,宣肺而不伤正。葶苈子治疗鼓胀的核心药物组合为"葶苈子-椒目-茯苓-吴茱萸-甘遂",代表方剂为葶苈茯苓丸。证型为水热蕴结证,其配伍特点为使峻下逐水,水有出路。葶苈子治疗痰饮的核心药物组合为"葶苈子-大黄-椒目-防己",代表方剂为己椒苈黄丸。证型为饮留胃肠证,其配伍特点为使苦辛宣泄,前后分消。
[Abstract]:Objective: the purpose of this paper is to sort out the prescriptions of Sophie Sophia in "Puji Fang" by collecting literature and statistical analysis, sum up the compatibility characteristics of "Puji Li", and summarize and analyze the literature of the herbs related to sophion in ancient Chinese literature. The research and development provides a broader idea and lays a foundation for the future research on the compatibility application of Sophia Sophia. Methods: using literature and statistics, there are 61739 prescriptions included in the "Pu Ji Fang", of which there are 654 prescriptions containing Sophia Sophia, accounting for 1.06% of the total number of prescriptions in the whole book, and the literature of the past generations of herbs. According to it, it is the first time to collect, collate, filter out the prescription containing Sophia Sophia and establish a database of prescription, and use the V2.5 statistical software to analyze the data of the database, cluster analysis, correlation analysis and so on. Finally, the results are analyzed and discussed. The common drugs for the compatibility of sophion are classified as purging drugs, expectorant antitussive antiasthmatic drugs, supplementing asthenia medicine, leothing and wetting medicine, etc. the common diseases in the treatment are edema, asthma, cough, swelling, sputum, lung carbuncle, lung distention, constipation, jaundice, accumulation and so on. The conclusion of this article is that Sophia leopara is combined with edema, asthma, coughing, swollen, phlegm drink, and so on five By analyzing the common diseases, the core drug of Sophia Sophia, which is the core drug for the treatment of edema, is a combination of "Sophia nexus - tetrandrine - Yu Li Ren tuckahoe - Chen peel" and a prescription for Sophie pills. White skin - pericarp - Glycyrrhiza ", the representative prescription is Yu Li Ren pill. The syndrome type is phlegm obstruction lung syndrome. The compatibility features of the syndrome are the reduction of the syndrome, the water wetting and the asthma can be leveled. The two core combination of sophion's treatment for coughing is" Sophia - Almond - almond - mulberry - Chen Peel - Glycyrrhiza "and" sophion - Ginseng - Ginseng - mume - poppy shell ", and the representative prescription is Chen orange powder. The syndrome type is the syndrome of phlegm dampness and dampness of lung syndrome and cold dampness attacking the lung syndrome. Its compatibility is a Xuan Yi San, which makes the evil have a way out and collect the lung without injury. The core drug combination for the bulging is "Sophia Zanthoxylum - tuckahoe - Evodia - sweet", and the representative prescription is tuckahoe pill. Syndrome type is water heat implication syndrome and its compatibility characteristics In order to make the water cut down, the water has a way out. The core drug combination of dracon seed treatment for sputum drink is "draca draca - Rhubarb - Zanthoxylum - tetrandrine", which represents the prescription for its own pepper and yellow pill.
【学位授予单位】：黑龙江中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R289.1

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