药罐疗法对腹型肥胖人群内脏脂肪代谢影响的临床研究

发布时间：2018-06-26 02:11

本文选题：腹型肥胖 + 腹部脂肪厚度　；参考：《北京中医药大学》2017年硕士论文

【摘要】：腹型肥胖又称"中心性肥胖"(或内脏型肥胖)是指脂肪过多的沉积在腹部或腹腔内脏。大量研究发现,腹型肥胖是2型糖尿病、高血压、高脂血症、脂肪肝等慢性病的危险因素。近年来腹型肥胖的人群越来越多,因此制定出有效的防治方案已经到了刻不容缓的地步。1研究目的本研究通过观察药罐疗法对腹型肥胖人群内脏脂肪代谢的临床疗效,探讨药罐疗法对腹型肥胖人群内脏脂肪代谢的影响及作用机理,为药罐疗法对腹型肥胖人群内脏脂肪代谢的有效性提供依据。2研究方法在2016年8月-2017年1月于北京中医药大学东方医院针灸科门诊就诊的患者中,选用符合入组标准的60例腹型肥胖受试者,并采取随机数字表法,随机分为治疗组30例,对照组30例。治疗组采用药罐疗法,一周治疗2次,整个疗程为8周,治疗期间要求受试者少食多餐,禁食油腻,多运动;对照组采用空白等待观察,对受试者不进行治疗,观察期间要求受试者少食多餐,禁食油腻,多运动,观察期8周结束后,可根据受试者的要求给予药罐补偿性治疗。研究者分别于治疗前后测量记录两组的各项指标,并运用统计软件SPSS20.0进行数据统计分析。3研究结果在本研究收入的60例受试者中,脱落与剔除者共6例,最终完成54例,其中治疗组27例,对照组27例。3.1腹部脂肪厚度及UVI比较药罐疗法组经治疗腹部皮下脂肪厚度(S1、S2)、内脏脂肪厚度(V1、V2)、左肝前脂肪厚度(AHF)、右肾周脂肪囊厚度(PRF)较治疗前有所下降,具有统计学意义(p0.05),内脏脂肪指数(UVI)治疗前后无明显差别(p0.05);空白等待观察组腹部脂肪厚度S1、V1、S2、V2、AHF、PRF及UVI观察前后无明显差异(p0.05);药罐疗法组治疗后与空白等待观察组观察后S1、V1、S2、V2、AHF、PRF具有明显差异(p0.05),UVI 无明显差异(p0.05)。治疗组 S1、V1、S2、V2、AHF、PRF 治疗前后差值与对照组观察前后差值比较具有显著性差别,具有统计学意义(p0.05),UVI差值无明显差异(p0.05)。3.2血清内脂素比较药罐疗法组血清内脂素治疗后较治疗前下降,具有统计学意义(P＜0.05);空白等待观察组血清内脂素观察前后无明显差异(p0.05);药罐疗法组治疗后与空白等待观察组观察后血清内脂素具有明显差异(p0.05)。治疗组血清内脂素治疗前后差值与对照组观察前后差值比较具有显著性差别,具有统计学意义(p0.05)。3.3简易体脂参数比较药罐疗法组经治疗体重(BW)、腰围(WC)、臀围(HC)、腰臀比(WHR)、体重指数(BMI)均比治疗前有所下降(p0.05);空白等待观察组BW、WC、BMI、WHR观察后数值增加,具有统计学意义(p0.05),HC观察前后无明显差异(p0.05);治疗组治疗后与对照组观察后HC、BMI有明显差别(p0.05),BW、WC、WHR无明显差异(p0.05),治疗组BW、WC、HC、WHR、BMI治疗前后差值与对照组观察前后差值比较具有显著性差别,具有统计学意义(p0.05)。3.4有效率比较经治疗,药罐疗法组受试者0例治愈,4例显效,20例有效,总有效率为88.9%,空白等待观察组受试者0例治愈,0例显效,8例有效,总有效率为29.6%,将两组的有效率进行比较,p0.05,两者具有显著性差别。4结论通过对这54例腹型肥胖受试者的临床研究发现,药罐疗法对改善腹型肥胖人群的内脏脂肪代谢具有良好的疗效。通过两组间的有效率比较,两组间的差异显著,提示药罐疗法是治疗腹型肥胖的一种安全有效的方法,临床可以加以推广使用。
[Abstract]:Abdominal obesity, also known as "central obesity" (or visceral obesity) refers to the deposition of fat in the abdomen or abdominal viscera. A large number of studies have found that abdominal obesity is a risk factor for chronic diseases such as type 2 diabetes, hypertension, hyperlipidemia, fatty liver and so on. In recent years, more and more people with abdominal obesity have developed effective prevention and control schemes. The objective of this study is to explore the effect of drug cupping therapy on visceral fat metabolism in obese people of abdominal type by observing the clinical effect of drug cupping therapy on visceral fat metabolism in obese people of abdominal type, and to explore the effect of drug can therapy on visceral fat metabolism in obese people of abdominal type, and to provide the basis for the study of.1..2 research In August 2016 -2017 years -2017 years in January in the Department of acupuncture and moxibustion at the Eastern Hospital of Beijing University of Chinese Medicine, the patients who were treated in the Department of acupuncture and moxibustion Department of the Eastern Hospital of Beijing University of Chinese Medicine were selected and randomly divided into 30 cases in the treatment group and 30 cases in the control group. The treatment group was treated with drug tank therapy, 2 times a week, and the whole course of treatment was 8 weeks. During the period of treatment, the subjects were required to eat less meal, fasting greasy and more exercise. The control group was not treated with a blank wait for observation. During the observation period, the subjects were asked to eat less meals, fasting and exercise more. After 8 weeks of observation, the patients could be treated according to the requirements of the subjects. The researchers were measured before and after the treatment. The indexes of two groups were recorded, and statistical software SPSS20.0 was used to analyze the results of data statistics and analysis (.3). Among the 60 subjects of this study, 6 cases were lost and eliminated, and 54 cases were finished. 27 cases in the treatment group and 27 cases of.3.1 in the control group were treated with the thickness of abdominal fat and the thickness of the abdominal subcutaneous fat (S1, compared with the UVI ratio. S2), the thickness of visceral fat (V1, V2), the thickness of the left prehepatic fat (AHF), the thickness of the right pericenal fat sac (PRF) was lower than that before the treatment (P0.05), and there was no significant difference (P0.05) before and after the treatment of visceral adipose index (UVI), and there was no significant difference between before and after the observation of the abdominal fat thickness in the blank waiting group. There were significant differences in S1, V1, S2, V2, AHF, PRF after the observation group was observed in the drug tank therapy group after the observation group was waiting for the observation group, and there was no significant difference in UVI (P0.05). The difference value before and after the treatment of the treatment group was significantly different from that of the control group before and after the observation. There was a significant difference between the difference values before and after the observation of the treatment group. Serum endogenous lipoprotein compared with the treatment group, serum endogenous lipoprotein was lower than before treatment, and had statistical significance (P < 0.05). There was no significant difference between before and after the observation of serum endogenous lipoprotein (P0.05) in the blank waiting group (P0.05) after the treatment group was treated with blank wait observation group (P0.05). The difference between before and after the treatment was significantly different from that of the control group before and after observation. The difference was statistically significant (P0.05).3.3 simple body fat parameters compared with the body weight (BW), waist circumference (WC), hip circumference (HC), waist to hip ratio (WHR), and body mass index (BMI) decreased (P0.05) compared with before treatment (P0.05); blank wait for observation group BW, WC, BMI, WHR view After observation, there was statistical significance (P0.05), and there was no significant difference between before and after HC observation (P0.05), and after the treatment group was treated with HC, BMI had significant difference (P0.05), BW, WC, WHR had no significant difference (P0.05). The difference value before and after treatment was significantly different from that of the control group before and after the treatment. Learning meaning (P0.05).3.4 was effective. 0 cases were cured, 4 cases were cured, 20 cases were effective, 20 cases were effective, the total effective rate was 88.9%. The blank waiting for the observation group was cured in 0 cases, 0 cases were cured, 8 cases were effective, the total effective rate was 29.6%, and the effective rate of the two groups was compared, P0.05, the significant difference.4 conclusion through this 54 The clinical study of abdominal obesity subjects found that drug cupping therapy has a good effect on improving visceral fat metabolism in abdominal obesity. Compared with the efficiency of the two groups, the difference between the two groups is significant, suggesting that the drug cupping therapy is a safe and effective method for the treatment of abdominal obesity and can be used in clinical practice.
【学位授予单位】：北京中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R244.3

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