排石颗粒配合盐酸坦洛新对输尿管软镜治疗大于2.0cm肾结石的疗效分析
发布时间：2018-08-04 08:24
【摘要】：目的:探讨排石颗粒配合盐酸坦洛新对电子输尿管软镜治疗大于2cm肾结石的临床疗效。方法:将2015年03月-2017年03月江苏大学附属医院90例应用输尿管软镜治疗直径大于2cm的肾石病患者按随机分配的方法分为实验组和对照组,每组各45例。实验组配合中药排石颗粒及盐酸坦洛新缓释片,对照组仅配合盐酸坦洛新。服药后每周复查一次,疗程四周或至排石干净。分别于第2周、第4周进行疗效判定。其观察指标为结石清除率、肾绞痛发生概率、结石的排净时间以及膀胱过度活动症(OABSS)评分。结果:1.实验组结石清除率为97.8%,而对照组的清除率为86.7%,差异具有统计学意义(P0.05);2.治疗组结石排净天数为(5.6±1.67)天,对照组结石排净天数为(12.7±2.63)天,差异具备统计学意义(P0.05);3.实验组术后发生肾绞痛概率为8.9%,而对照组术后发生肾绞痛概率为24.4%,差异具备统计学意义(P0.05);4.实验组OABSS评分为(5.3±1.19),对照组OABSS评分为(11.2±2.67),差异具有统计学意义(P0.05)。结论:排石颗粒配合盐酸坦洛新对电子输尿管软镜治疗大于2.0cm结石患者具有结石清除率高、肾绞痛发生概率小、结石排出时间短以及并发症少的治疗优势。
[Abstract]:Objective: to investigate the clinical effect of Paishi granule combined with Tanluoxin Hydrochloride in the treatment of renal calculi larger than 2cm by electronic ureteroscopy. Methods: from March 2015 to March 2017, 90 patients with nephrolithiasis whose diameter was larger than 2cm were divided into experimental group (n = 45) and control group (n = 45). The experimental group combined with Paishi granules and Tanluoxin Hydrochloride sustained release tablets, while the control group only combined with Tanluoxin Hydrochloride. Recheck once a week after taking the medicine, the course of treatment or until the stone clean. The curative effect was evaluated at week 2 and week 4 respectively. The parameters were stone clearance rate, probability of occurrence of renal colic, time of stone removal and (OABSS) score of bladder hyperactivity. The result is 1: 1. The stone clearance rate of the experimental group was 97.8, while that of the control group was 86.7. The difference was statistically significant (P0.05). The days of stone drainage were (5.6 卤1.67) days in the treatment group and (12.7 卤2.63) days in the control group. The difference was statistically significant (P0.05). The probability of renal colic in the experimental group was 8.9 and that in the control group was 24.40.The difference was statistically significant (P0.05). The OABSS score was (5.3 卤1.19) in the experimental group and (11.2 卤2.67) in the control group (P0.05). Conclusion: Paishi granule combined with Tanluoxin Hydrochloride has the advantages of high removal rate of calculi, low probability of occurrence of renal colic, short time of stone excretion and fewer complications in patients with soft endoscopy of electronic ureter than in patients with 2.0cm calculi.
【学位授予单位】：江苏大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R699.2
本文编号：2163230
[Abstract]:Objective: to investigate the clinical effect of Paishi granule combined with Tanluoxin Hydrochloride in the treatment of renal calculi larger than 2cm by electronic ureteroscopy. Methods: from March 2015 to March 2017, 90 patients with nephrolithiasis whose diameter was larger than 2cm were divided into experimental group (n = 45) and control group (n = 45). The experimental group combined with Paishi granules and Tanluoxin Hydrochloride sustained release tablets, while the control group only combined with Tanluoxin Hydrochloride. Recheck once a week after taking the medicine, the course of treatment or until the stone clean. The curative effect was evaluated at week 2 and week 4 respectively. The parameters were stone clearance rate, probability of occurrence of renal colic, time of stone removal and (OABSS) score of bladder hyperactivity. The result is 1: 1. The stone clearance rate of the experimental group was 97.8, while that of the control group was 86.7. The difference was statistically significant (P0.05). The days of stone drainage were (5.6 卤1.67) days in the treatment group and (12.7 卤2.63) days in the control group. The difference was statistically significant (P0.05). The probability of renal colic in the experimental group was 8.9 and that in the control group was 24.40.The difference was statistically significant (P0.05). The OABSS score was (5.3 卤1.19) in the experimental group and (11.2 卤2.67) in the control group (P0.05). Conclusion: Paishi granule combined with Tanluoxin Hydrochloride has the advantages of high removal rate of calculi, low probability of occurrence of renal colic, short time of stone excretion and fewer complications in patients with soft endoscopy of electronic ureter than in patients with 2.0cm calculi.
【学位授予单位】：江苏大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R699.2
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