安神宁动颗粒治疗儿童多动症—肝肾阴虚证的临床疗效观察

发布时间：2018-12-20 18:53

【摘要】：目的:与西药治疗作对照,运用中药安神宁动颗粒治疗儿童多动症之肝肾阴虚证,以期从中医角度分析儿童多动症,观察及分析安神宁动颗粒治疗本病的临床疗效。方法:按照随机、对照的原则,60例患儿符合纳入标准,随机分为两组,即中药组、西药对照组,各30例。两组均进行6周的系统治疗。治疗前以及治疗之后分别对三大常规、肝肾功能以及心电图做一次检测,评估安全性,若有不良事件发生,则分析处理。6周后对总疗效及主要症状(注意力涣散、多动冲动)改善情况进行对比。对发生的不良事件做相关记录。结果:1.治疗组总有效率86.7%,对照组83.3%,经秩和检验,P0.05,差异无统计学意义。2.治疗组和对照组治疗多动症之注意力涣散症状积分组内比较,经t检验,两者均P0.01,差异有高度统计学意义。两组组间进一步比较,P0.05,差异无统计学意义。3.治疗组和对照组治疗多动症之多动、冲动症状积分组内比较,经t检验,两者均P0.01,差异有高度统计学意义。两组组间进一步比较,P0.05,差异具有统计学意义。4.两组在治疗过程中都未曾出现不良的副反应。结论:1.中药组、对照组治疗本病的总疗效相当;2.中药组在改善多动、冲动症状方面优于对照组。3.安神宁动颗粒治疗儿童多动症肝肾阴虚证有效,尤其可改善儿童多动症多动、冲动症状。
[Abstract]:Objective: to observe and analyze the clinical effect of Anshenning action granule in treating children's hyperactivity syndrome (ADHD) from the point of view of traditional Chinese medicine (TCM) by using Anshenning granule to treat the syndrome of deficiency of liver and kidney yin in children with hyperactivity syndrome (ADHD). Methods: according to the principle of randomization and control, 60 children were randomly divided into two groups: the traditional Chinese medicine group and the western medicine control group, each with 30 cases. Both groups were treated systematically for 6 weeks. Before and after treatment, the three major routine, liver and kidney function and electrocardiogram were tested to evaluate the safety, and if there were adverse events, the treatment was analyzed and dealt with. Hyperactive impulse) improvement is compared. Record adverse events. Results: 1. The total effective rate of the treatment group was 86.7%, while that of the control group was 83.3%. By rank sum test, the difference was not statistically significant (P 0.05). There was a significant difference between the treatment group and the control group in the score of attention deficit disorder (ADHD). By t test, the difference was statistically significant between the two groups (P0.01). Further comparison between the two groups, P0.05, the difference was not statistically significant. The scores of hyperactivity and impulsive symptoms in the treatment group and the control group were compared with each other by t test (P 0.01), the difference was statistically significant. Further comparison between the two groups, P0.05, the difference was statistically significant. There were no adverse reactions in both groups during the course of treatment. Conclusion: 1. Chinese medicine group, control group, the total efficacy of the treatment of this disease is similar; 2. Chinese medicine group in improving hyperactivity, impulse symptoms than the control group. 3. 3. Anshenning granule is effective in treating children with hyperactivity syndrome of liver and kidney yin deficiency, especially in improving hyperactivity and impulsive symptoms in children with ADHD.
【学位授予单位】：南京中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R277.7

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