不同重建方法和成像方式在提高CTU图像质量方面的应用研究
发布时间：2019-05-29 05:12
【摘要】：研究背景与目的自泌尿系统CT成像(computed tomography urograpy,CTU)应用于临床日常工作以来,已替代静脉肾盂造影(IVU)成为评估血尿患者病因的首要影像学检查方法。然而传统CTU排泄期高浓度碘对比剂所造成的硬化性伪影,对于泌尿系统自身解剖结构及相关病灶的显示,降低了对比剂周围组织的清晰度,严重影响图像质量。故本研究从降低CTU硬化性伪影出发,比较滤波反投影法(FBP)、自适应统计迭代重建法(ASi R)、能谱单能量成像(85 ke V)及呋塞米改良法下的CTU图像上肾盂、肾盏旁硬化性伪影的大小,探索不同成像技术及图像重建方法在降低CTU硬化性伪影方面的作用,从而提高CTU图像质量。材料和方法:40例患者采用能谱GE Discovery CT750 HD(GE Healthcare)扫描仪,常规CTU动静脉期、排泄期扫描,扫描结束后,切换成GSI扫描模式扫描排泄期,范围均自膈顶至耻骨联合下缘。对常规扫描模式下图像选取排泄期数据分别采用FBP、ASIR30%重建,GSI扫描模式下选取85 Kev。数据重建厚度均为0.625 mm,将图像传至GE AW 4.51工作站。收集我院行小剂量呋塞米改良法CTU成像患者32例。32例小剂量呋塞米改良法:行小剂量呋塞米改良法扫描,结束后采用FBP重建,重建厚度0.625 mm,将图像传至GE AW 4.51工作站。对以上所取得图像采用VR、MPR、MIP、CPR等方法行尿路成像后处理,图像测量并比较肾盂、肾盏硬化性伪影较严重层面肾盏旁肾脏图像的噪声(SD)、信噪比(SNR)、对比噪声比(CNR)、背景噪声及肾盂、肾盏旁硬化性伪影(BHA)及输尿管连续性相关主、客观方面评分。结果1.肾盂、肾盏旁硬化性伪影主观评分方面,传统FBP组、传统ASIR组、能谱组、改良组评分分别为1.30±0.46,1.40±0.49,2.53±0.50和2.81±0.47。2.传统FBP组、传统ASIR组、能谱组、改良组SD分别40.25±7.80,33.84±6.92,19.89±5.22,29.36±6.98,与传统FBP比较,传统ASIR组较其降低了约16%,能谱组降低约51%,改良组降低约27%。3.传统FBP组、传统AISR组、能谱组、改良组SNR分别约为3.88±0.77,4.69±0.94,5.51±1.21,6.88±2.02,与传统FBP组比较,传统ASIR组较其增加约21%,能谱组增加约42%,改良组增加约77%。4.传统FBP组、传统ASIR组、能谱组、改良组CNR分别为8.19±1.35,9.87±1.64,11.36±1.60,12.50±3.17,与传统FBP组相比,传统ASIR组较其增加约21%,能谱组增加约39%,改良组增加约53%。5.在输尿管连续性评分方面,呋塞米改良组明显优于其他三组。结论:改良法降低CTU排泄期硬化性伪影效果最佳,其次是能谱成像。能谱成像能够明显提高图像质量。输尿管连续性显示改良法效果最佳。
[Abstract]:Background and objective since the application of urinary system CT imaging (computed tomography urograpy,CTU in clinical daily work, intravenous pyelography (IVU) has become the primary imaging method to evaluate the etiology of hematuria. However, the sclerosing artifacts caused by high concentration iodine contrast agent in the excretion stage of CTU reduce the clarity of the tissue around the contrast agent and seriously affect the image quality by displaying the anatomical structure of the urinary system and related lesions. Therefore, in order to reduce the sclerosing artifact of CTU, the filtering backprojection (FBP), adaptive statistical iterative reconstruction method (ASi R), energy spectrum single energy imaging (85 ke V) and furosemide modified CTU image on the renal pelvis) was compared in this study. To explore the role of different imaging techniques and image reconstruction methods in reducing CTU sclerosing artifacts, so as to improve the image quality of CTU. Materials and methods: 40 patients were scanned with energy spectrum GE Discovery CT750 HD (GE Healthcare) scanner, conventional CTU arteriovenous phase and excretion phase. After scanning, they were switched to GSI scanning mode, ranging from the phrenic apex to the inferior edge of pubic symphysis. The excretion period data were reconstructed by FBP,ASIR30% in conventional scanning mode and 85 Kev. in GSI scanning mode. The data reconstruction thickness is 0.625 mm, and the image is transmitted to GE AW 4.51 workstation. 32 patients with low dose furosemide modified CTU imaging in our hospital were collected. 32 patients with low dose furosemide modified method were scanned by low dose furosemide modified method. FBP reconstruction was performed at the end of the study. The reconstruction thickness was 0.625 mm,. Send the image to GE AW 4.51 workstation. VR,MPR,MIP,CPR and other methods were used for post-processing of urography. The noise (SD), signal-to-noise ratio (SNR) of renal pelvis and calyceal sclerosing artifacts were measured and compared with those of renal pelvis and calyceal sclerosing artifacts. The subjective and objective scores of background noise and renal pelvis, parachal sclerosing artifact (BHA) and Ureteral continuity were compared with (CNR), background noise and renal pelvis, parachal sclerosing artifact (BHA) and Ureteral continuity. Result 1. The scores of traditional FBP group, traditional ASIR group, energy spectrum group and improved group were 1.30 卤0.46, 1.40 卤0.49, 2.53 卤0.50 and 2.81 卤0.47.2, respectively. The SD of the traditional FBP group, the traditional ASIR group, the energy spectrum group and the improved group were 40.25 卤7.80,33.84 卤6.92, 19.89 卤5.22 and 29.36 卤6.98, respectively. Compared with the traditional FBP group, the traditional ASIR group decreased by about 16%, and the energy spectrum group decreased by about 51%. The improvement group decreased by about 27%. 3. The SNR of the traditional FBP group, the traditional AISR group, the energy spectrum group and the improved group were about 3.88 卤0.77, 4.69 卤0.94, 5.51 卤1.21 and 6.88 卤2.02, respectively. Compared with the traditional FBP group, the traditional ASIR group increased by about 21%, and the energy spectrum group increased by about 42%. The improvement group increased by about 77%. 4. The CNR of the traditional FBP group, the traditional ASIR group, the energy spectrum group and the improved group were 8.19 卤1.35, 9.87 卤1.64, 11.36 卤1.60 and 12.50 卤3.17, respectively. Compared with the traditional FBP group, the traditional ASIR group increased by about 21%, and the energy spectrum group increased by about 39%. The improvement group increased by about 53%. 5. 5%. In terms of ureter continuity score, furosemide modified group was significantly better than the other three groups. Conclusion: the improved method has the best effect on reducing sclerosing artifacts during excretion of CTU, followed by energy spectrum imaging. Energy spectrum imaging can obviously improve the image quality. The improved method has the best effect on the continuous display of ureter.
【学位授予单位】：安徽医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R816.7
[Abstract]:Background and objective since the application of urinary system CT imaging (computed tomography urograpy,CTU in clinical daily work, intravenous pyelography (IVU) has become the primary imaging method to evaluate the etiology of hematuria. However, the sclerosing artifacts caused by high concentration iodine contrast agent in the excretion stage of CTU reduce the clarity of the tissue around the contrast agent and seriously affect the image quality by displaying the anatomical structure of the urinary system and related lesions. Therefore, in order to reduce the sclerosing artifact of CTU, the filtering backprojection (FBP), adaptive statistical iterative reconstruction method (ASi R), energy spectrum single energy imaging (85 ke V) and furosemide modified CTU image on the renal pelvis) was compared in this study. To explore the role of different imaging techniques and image reconstruction methods in reducing CTU sclerosing artifacts, so as to improve the image quality of CTU. Materials and methods: 40 patients were scanned with energy spectrum GE Discovery CT750 HD (GE Healthcare) scanner, conventional CTU arteriovenous phase and excretion phase. After scanning, they were switched to GSI scanning mode, ranging from the phrenic apex to the inferior edge of pubic symphysis. The excretion period data were reconstructed by FBP,ASIR30% in conventional scanning mode and 85 Kev. in GSI scanning mode. The data reconstruction thickness is 0.625 mm, and the image is transmitted to GE AW 4.51 workstation. 32 patients with low dose furosemide modified CTU imaging in our hospital were collected. 32 patients with low dose furosemide modified method were scanned by low dose furosemide modified method. FBP reconstruction was performed at the end of the study. The reconstruction thickness was 0.625 mm,. Send the image to GE AW 4.51 workstation. VR,MPR,MIP,CPR and other methods were used for post-processing of urography. The noise (SD), signal-to-noise ratio (SNR) of renal pelvis and calyceal sclerosing artifacts were measured and compared with those of renal pelvis and calyceal sclerosing artifacts. The subjective and objective scores of background noise and renal pelvis, parachal sclerosing artifact (BHA) and Ureteral continuity were compared with (CNR), background noise and renal pelvis, parachal sclerosing artifact (BHA) and Ureteral continuity. Result 1. The scores of traditional FBP group, traditional ASIR group, energy spectrum group and improved group were 1.30 卤0.46, 1.40 卤0.49, 2.53 卤0.50 and 2.81 卤0.47.2, respectively. The SD of the traditional FBP group, the traditional ASIR group, the energy spectrum group and the improved group were 40.25 卤7.80,33.84 卤6.92, 19.89 卤5.22 and 29.36 卤6.98, respectively. Compared with the traditional FBP group, the traditional ASIR group decreased by about 16%, and the energy spectrum group decreased by about 51%. The improvement group decreased by about 27%. 3. The SNR of the traditional FBP group, the traditional AISR group, the energy spectrum group and the improved group were about 3.88 卤0.77, 4.69 卤0.94, 5.51 卤1.21 and 6.88 卤2.02, respectively. Compared with the traditional FBP group, the traditional ASIR group increased by about 21%, and the energy spectrum group increased by about 42%. The improvement group increased by about 77%. 4. The CNR of the traditional FBP group, the traditional ASIR group, the energy spectrum group and the improved group were 8.19 卤1.35, 9.87 卤1.64, 11.36 卤1.60 and 12.50 卤3.17, respectively. Compared with the traditional FBP group, the traditional ASIR group increased by about 21%, and the energy spectrum group increased by about 39%. The improvement group increased by about 53%. 5. 5%. In terms of ureter continuity score, furosemide modified group was significantly better than the other three groups. Conclusion: the improved method has the best effect on reducing sclerosing artifacts during excretion of CTU, followed by energy spectrum imaging. Energy spectrum imaging can obviously improve the image quality. The improved method has the best effect on the continuous display of ureter.
【学位授予单位】：安徽医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R816.7
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