居室内装饰材料的致突变作用

发布时间：2019-04-22 21:56

【摘要】：目的研究装饰材料挥发性化合物对实验动物和暴露人群的致突变作用,从而为室内装饰材料安全卫生质量的管理提供技术依据。方法根据监测装修后客房空气挥发物浓度,在染毒柜内配制相当于现场测得的5、10、20、40倍浓度进行小鼠微核试验;分别检测在装修环境中工作的女服务员的外周血淋巴细胞微核发生率。结果装修半年内室内空气中甲醛、苯、甲苯、二甲苯、乙酸乙酯、乙酸丁酯的含量明显高于未装修的客房,井且高于国家标准;动物实验结果表明,于现场浓度40倍剂量对小鼠染毒15d后,其微核率比阴性对照高,且差异有显著性（P0.005）。在装修与未装修客房内工作的女服务员外周血微核率则差异无显著性（P0.05）。结论装
[Abstract]:Aim to study the mutagenic effect of volatile compounds of decorative materials on experimental animals and exposed population, so as to provide technical basis for the management of safety and hygiene quality of interior decorative materials. Methods according to the concentration of air volatiles in the rooms after decoration, the micronucleus test of mice was carried out at the concentration of 5, 10, 20 and 40 times of the concentration measured on the spot in the exposure cabinet. The frequencies of micronuclei in peripheral blood lymphocytes of waitresses working in decorated environment were detected respectively. Results the contents of formaldehyde, benzene, toluene, xylene, ethyl acetate and butyl acetate in indoor air within half a year were significantly higher than those in undecorated guest rooms and wells and higher than national standards. The results of animal experiment showed that the micronucleus rate of mice exposed to 40-fold dose was higher than that of negative control for 15 days, and the difference was significant (P0.005). There was no significant difference in the rate of peripheral blood micronucleus between the waitresses working in decorated and undecorated rooms (P0.05). Conclusion assembly
【作者单位】：深圳市卫生防疫站深圳市卫生防疫站深圳市卫生防疫站深圳市卫生防疫站深圳市卫生防疫站深圳市卫生防疫站深圳市卫生防疫站
【基金】：深圳市科技基金资助项目（1999[04040]）
【分类号】：X831

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