动态突触、神经耦合与时间延迟对神经元发放的影响

发布时间：2018-01-27 05:59

本文关键词： 神经元突触刺激傅里叶变换延迟　出处：《物理学报》2017年20期 　论文类型：期刊论文

【摘要】：神经元膜电位的受激发放在神经系统的信息传递中起着重要作用.基于一个受动态突触刺激的突触后神经元发放模型,采用数值模拟和傅里叶变换分析的方法研究了动态突触、神经耦合与时间延迟对突触后神经元发放的影响.结果发现:突触前神经元发放频率与Hodgkin-Huxley神经元的固有频率发生共振决定了突触后神经元发放的难易,特定频率范围内的电流刺激有利于神经元激发,动态突触输出的随机突触电流中这些电流刺激所占的比率在很大程度上影响了突触后神经元的发放次数;将突触后神经元换成神经网络后,网络中神经元之间的耦合可以促进神经元的发放,耦合中的时间延迟可以增强这种促进作用,但是不会改变神经耦合对神经元发放的促进模式.
[Abstract]:The activation of neuronal membrane potentials plays an important role in the transmission of information in the nervous system, based on a postsynaptic neuronal release model stimulated by dynamic synapses. Dynamic synapses were studied by numerical simulation and Fourier transform analysis. Effects of neural coupling and time delay on postsynaptic neuronal release. The resonance between the frequency of presynaptic neurons and the intrinsic frequency of Hodgkin-Huxley neurons determines the difficulty of postsynaptic neurons. Current stimulation in the specific frequency range is beneficial to the excitation of neurons. The proportion of these current stimuli in the random synaptic current output from dynamic synapses largely affects the number of postsynaptic neurons. After replacing postsynaptic neurons with neural networks, the coupling between neurons in the network can promote the firing of neurons, and the time delay in the coupling can enhance this effect. But it does not change the pattern of neural coupling that stimulates the release of neurons.
【作者单位】：中国矿业大学物理学院;
【基金】：中央高校基本科研业务费(批准号:2015XKMS080(TJ))资助的课题~~
【分类号】：R338
【正文快照】： 之间传递的[25].在神经信息的传递中,突触具有1引言很强的变异性[26],化学浓度的变化与空间异质性都能导致突触的电导在短时间内波动,形成动态处理和传递信息的神经系统由大量的神经元突触.在大脑中,突触传递神经信息的过程中会出个体构成,神经信号是编码在神经元的动作电位之

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