干细胞实现汗腺再生的机制分析

发布时间：2018-04-04 13:42

  本文选题：皮肤附属器官　切入点：同种异体皮　出处：《感染、炎症、修复》2016年03期

【摘要】：正汗腺是重要的皮肤附属器官,它主要通过汗液排泄调节机体的体温,参与物质代谢并维持体液平衡。汗腺发育是一个复杂的过程,汗腺一旦被破坏则不能再生。世界上每年有数百万的烧伤患者,其中大面积深度烧伤患者,损伤深至真皮深层或皮肤全层,此时创面的汗腺组织损伤无法修复,严重影响患者的排汗功能和生活质量[1]。然而常见的同种异体皮覆盖创面的治疗并没有涉及到汗腺功能的修复,患者无法排汗的痛苦没有得到解决。汗腺移植的研究为大面积深
[Abstract]:Positive sweat gland is an important subsidiary organ of skin. It regulates body temperature through sweat excretion, participates in substance metabolism and maintains humoral balance.Sweat gland development is a complex process, sweat glands once destroyed can not regenerate.There are millions of burn patients in the world every year, of which a large area of deep burn patients, the damage to the deep dermis or the whole skin layer, at this time, the wound sweat gland tissue damage can not be repaired, seriously affect the sweating function of patients and quality of life [1].However, the treatment of common allogeneic skin covering wounds does not involve the repair of sweat gland function, and the patient's pain of not being able to perspire has not been resolved.The study of sweat gland transplantation is deep in large area
【作者单位】： 解放军总医院基础医学研究所;解放军总医院第一附属医院全军创伤修复与组织再生重点实验室;
【基金】：国家自然科学基金资助项目(81571905,81171798,81421064,81230041) 北京市自然科学基金资助项目(7142124) 国家973计划资助项目(2012CB518105)
【分类号】：R329.2
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本文编号：1710195