A型行为者应激反应相似性的研究

发布时间：2018-03-01 03:17

  本文关键词： 应激相似性 应激 中性粒细胞 A型行为者 皮质醇与甲状腺激素 血压　出处：《安徽医科大学》2005年硕士论文　论文类型：学位论文

【摘要】：目的 探讨医科学生A行为类型与应激反应的特征;①A和B行为者安静与应激时血浆皮质醇(cortisol)和甲状腺激素(T_3,T_4)反应的特征,以及行为因子与血浆皮质醇(cortisol)反应的特征的关系;②A和B行为者安静与应激时中性粒细胞吞噬功能的变化特征;③A和B行为者安静与应激时外周心血管反应的特征。 方法 采用A型行为类型量表将75名医科学生测量分型后;在以限时心算测验为应激原下,在3-5min完成血液样本的采集,立即送检;1周后安静状态再次采血样送检;经放射免疫法分别测定血浆皮质醇和甲状腺激素水平值;分别运动前,运动中,运动后采集血样,采用化学发光法测定他们的中性粒细胞吞噬功能变化;在考试应激状态与安静状态下,测量血压的变化。采用逻辑质的方法分析相互的逻辑关系。 结果①在安静时,A型和B型行为者应激时血浆皮质醇水平的差值Acortisol(应激值-安静值)有显著差异性(t=2.376,P0.05);A型行为者应激时血浆T3水平比安静时显著减少(t=2.875,P0.01);全体A型和B型应激时T4水平比安静时显著减少(t=2.687,P0.01)。②对于A型行为者,安静状态,非运动组的中性粒细胞吞噬功能较运动组强(t=2.132,P0.05),而在运动中和运动后两种状态下,运动型组的增幅均明显高于非运动型组(P0.01);在运动员和非运动员应激反应时中性粒细胞吞噬功能强度也有显著逻辑差异(t=0.2106,P0.05;t≥3.9713,P0.05)。在考试应激时,A型脉压比B型的减小。A型和B型组外周心血管反应指标血压变化比较有显著逻辑差异(t=11.001,P0.01;t≤1.920,P0.05)。③分别在应激和安静时,其cortisol和T3指标之间均无统计差异(应激t≤0.05058,安静t≤1.1095,均P0.05);每项指标(cortisol或T_3)在A型和B型行为者间应激反应差别具有显著差性(cortisol:t=2.373,P0.05;t≥2.843,P0.05;T3:t≥4.744,P0.05,t=0.000, P0.05),两种指标的逻辑性相同即相似性:同时比较A型和B型行为者应激反应的差值Acortisol和△T_4指标
[Abstract]:Objective to investigate the characteristics of A behavior type and stress response in medical students. Relationship between behavioral factors and characteristics of plasma cortisol cortisol response the changes of neutrophil phagocytosis in quiet and B actors during stress the characteristics of neutrophil phagocytosis during stress and the characteristics of peripheral cardiovascular response in quiet and B behaviors. Methods Seventy-five medical students were measured and classified by type A behavioral type scale, and blood samples were collected in 3-5 minutes under the stress of time-limited mental arithmetic test, and blood samples were collected again in a quiet state after one week's examination. Plasma cortisol and thyroid hormone levels were measured by radioimmunoassay, blood samples were collected before, during and after exercise respectively, and the phagocytic function of neutrophils was measured by chemiluminescence method. The changes of blood pressure were measured in the state of test stress and quietness, and the logical relationship between them was analyzed by the method of logical quality. Results 1There were significant differences in plasma cortisol levels between patients with type A and type B behaviors under stress. There was a significant difference in plasma cortisol levels between patients with type A and type B behaviors under stress. Plasma T3 levels in patients with type A behavior under stress were significantly lower than those in patients with type A behavior under quiet stress, and the levels of plasma cortisol in all patients with type A and type B behavior were significantly lower than those in patients with type A and type B behaviors under quiet stress. All patients with type A and type B behavior had significant differences in plasma cortisol levels. The level of T4 in type B stress was significantly lower than that in quiet stress. In quiet state, the phagocytosis of neutrophils in the non-exercise group was stronger than that in the exercise group, while in the exercise and post-exercise states, the phagocytosis of neutrophil was stronger than that in the exercise group. The increase rate of neutrophil phagocytosis in the exercise type group was significantly higher than that in the non-exercise type group, and the phagocytosis intensity of neutrophils was significantly different between athletes and non-athletes in the stress response. The pulse pressure ratio B of type A was decreased during test stress. There was a significant logical difference in the changes of blood pressure between type A and type B groups in peripheral cardiovascular response, and there were significant differences between the two groups in stress and quiet, respectively, when the changes of blood pressure were 11.001U, P0.01t 鈮，

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