回肠代膀胱家兔模型制作中不同的麻醉药物

发布时间：2018-03-19 19:49

  本文选题：回肠　切入点：膀胱　出处：《中国组织工程研究》2014年49期 　论文类型：期刊论文

【摘要】：背景:家兔回肠代膀胱模型制作对麻醉要求较高,需要手术野清晰,术毕恢复迅速,麻醉药物及方法的选择不影响肠道平滑肌的蠕动。目的:比较水合氯醛和乌拉坦对家兔回肠代膀胱模型制作的麻醉效果。方法:18只家兔随机等分为乌拉坦组和水合氯醛组,分别用体积分数10%水合氯醛2 m L/kg和体积分数20%乌拉坦5 m L/kg实施耳缘静脉麻醉后,于原膀胱外1 cm处离断双输尿管,种植于回盲部10 cm处切取的15 cm肠段,建立回肠代膀胱模型。结果与结论:2组家兔麻醉后心率均较麻醉前出现明显下降(P≤0.05),但2组间差异无显著性意义(P0.05)。与水合氯醛组相比,乌拉坦组兔被麻醉的持续时间、苏醒时间过长,死亡率高。说明水合氯醛是适合家兔回肠代膀胱模型制作的安全长效的麻醉剂。
[Abstract]:Background: the rabbit model of ileal replacement of bladder requires high anesthesia, a clear surgical field and a rapid recovery at the end of the operation. The choice of anesthetic drugs and methods had no effect on the peristalsis of intestinal smooth muscle. Objective: to compare the anesthetic effects of chloral hydrate and urartan on rabbit ileal bladder replacement model. Methods: 18 rabbits were randomly divided into two groups: uratan group and chloral hydrate group. After intravenous anaesthesia with volume fraction 10% mL / kg of chloral hydrate 2 mL / kg and volume fraction 20% mL / kg of uratan 5 mL / kg, the ureter was cut off at 1 cm outside the original bladder and implanted in the 15 cm intestinal segment removed from the ileocecal region 10 cm. Results and conclusion the heart rate of two groups of rabbits decreased significantly after anesthesia than that before anesthesia (P 鈮，

本文编号：1635744