基于光学相干层析技术的葡萄糖浓度测量研究

发布时间：2018-05-09 07:38

本文选题：光学相干层析成像(OCT) + 葡萄糖溶液浓度　；参考：《光电子·激光》2014年11期

【摘要】：使用迈克尔逊干涉仪,针对光学相干层析成像(OCT,optical coherence tomography)非侵入性成像的特点,设计并建立了一种OCT系统。使用建立的OCT系统测量生理水平上葡萄糖溶液的浓度,研究干涉图像波面的最高点与最低点之间的距离和样品浓度的相关情况。在实验室条件下,使用5%葡萄糖溶液和生理盐水得到生理水平的测量样品,测量结果的线性系数达到0.999 8,方差为0.003 9。实验结果表明,使用OCT系统,利用干涉图像波面的最高点与最低点之间的距离和样品浓度的相关性能精确快速测出葡萄糖溶液的浓度,为糖尿病患者的血糖无损监测提供了一种新思路。
[Abstract]:According to the characteristics of optical coherence tomography (Oct) optical coherence tomography, a OCT system is designed and established by using Michelson interferometer. The concentration of glucose solution at physiological level was measured by using the established OCT system to study the distance between the highest and lowest points of the wave surface of the interference image and the correlation of the concentration of the sample. Under laboratory conditions, the physiological level of the samples was obtained by using 5% glucose solution and physiological saline. The linear coefficient and variance of the measurement results were 0.999 8 and 0.003 9 respectively. The experimental results show that the concentration of glucose solution can be measured accurately and quickly by using the OCT system, using the distance between the highest and lowest points of the interference image wave surface and the correlation of the sample concentration. It provides a new idea for nondestructive monitoring of blood glucose in diabetic patients.
【作者单位】：陕西师范大学物理学与信息技术学院;西安石油大学理学院;西安交通大学机械工程学院;
【基金】：国家自然科学基金委员会与中国民航局联合资助(U1233116) 高等学校博士学科点专项科研基金(2012020111032) 西安石油大学博士科研基金(2014BS42)资助项目
【分类号】：R312

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