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广州市学龄儿童红细胞分布宽度与血压水平的相关性

发布时间:2018-01-31 18:22

  本文关键词: 红细胞 血压 回归分析 儿童 出处:《中国学校卫生》2017年10期  论文类型:期刊论文


【摘要】:目的探讨广州市6~11岁学龄儿童红细胞分布宽度(red blood cell volume distribution width,RDW)与血压水平的相关性,为有效预防控制学龄儿童高血压提供参考。方法采用整群抽样的方法抽取广州市6~11岁学龄儿童6 188名,对调查对象进行血压测量和静脉全血细胞分析,分别获得收缩压、舒张压、红细胞数量、血红蛋白和RDW等指标,采用Pearson相关分析和逐步线性回归等方法进行统计分析。结果广州市6~11岁学龄儿童RDW中位数为13.3%,男生(13.4%)高于女生(13.3%)(Z=8.609,P0.01);收缩压的中位数为100 mm Hg,舒张压中位数为64 mm Hg;高血压和高血压前期组学龄儿童RDW高于血压正常组的儿童(H=15.400,P0.05)。Pearson相关分析显示,RDW与收缩压和红细胞数均呈正相关(r值分别为0.044,0.465,P值均0.01),与血红蛋白呈负相关(r=-0.219,P0.01)。多元线性逐步回归显示,收缩压是RDW的影响因素之一(B=0.002,P=0.008)。结论 RDW在高血压和高血压前期学龄儿童中增高,且与收缩压存在关联。
[Abstract]:Objective to study the red blood cell volume distribution width in children aged 6 to 11 years old in Guangzhou. The correlation between RDW) and blood pressure level provides a reference for the effective prevention and control of hypertension in school-age children. Methods 6 188 children aged 11 years old in Guangzhou were selected by cluster sampling. Systolic blood pressure, diastolic blood pressure, erythrocyte count, hemoglobin and RDW were obtained by blood pressure measurement and venous whole blood cell analysis. Pearson correlation analysis and stepwise linear regression were used for statistical analysis. Results the median RDW of children aged 6 to 11 in Guangzhou was 13.3%. The ratio of 13.4% for male students was higher than that for girls (8.609% P0.01); The median systolic blood pressure and diastolic blood pressure were 100 mm Hg and 64 mm Hg respectively. The RDW of school age children in hypertension and prehypertension group was higher than that in normal blood pressure group (P 0.05N. Pearson). RDW was positively correlated with systolic blood pressure (SBP) and erythrocyte count (r = 0.044) and negatively correlated with hemoglobin (P = 0.01). Multiple linear stepwise regression analysis showed that systolic blood pressure was one of the influencing factors of RDW. Conclusion RDW is higher in hypertension and prehypertensive school-age children, and is associated with systolic blood pressure (SBP).
【作者单位】: 广东省广州市中小学卫生健康促进中心;
【分类号】:R725.4
【正文快照】: 红细胞体积分布宽度(red blood cell volume distri-bution width,RDW)是反映外周血红细胞体积异质性的参数,由血细胞分析仪测量而获得[1]。随着全血细胞分析仪在我国的普及应用,RDW已成为血液常规检测的参数之一,常用于贫血和鉴别诊断[2-5]。近年研究发现,RDW增高在心血管疾

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