新生儿红斑狼疮病例报告与文献复习

发布时间：2018-02-28 04:36

本文关键词： 新生儿红斑狼疮诊断鉴别诊断　出处：《广西医科大学》2012年硕士论文　论文类型：学位论文

【摘要】：目的：为了提高临床医生对新生儿红斑狼疮的认识,进一步提高新生儿红斑狼疮的诊疗质量。方法：对2例非临床红斑狼疮或干燥综合征患者所生的新生儿红斑狼疮患儿的临床病历资料进行分析总结,并结合相关文献讨论其发病病因、临床特点、组织病理学特征、诊断、鉴别诊断及治疗。结果：根据2例新生儿的皮疹特点,患儿及生母ANA(±)、抗ENA：抗Ro/SSA(+).抗La/SSB(+),以及皮肤病理改变,并与其它有类似I临床表现的皮肤病进行鉴别,诊断新生儿红斑狼疮成立。结论：新生儿狼疮临床上少见,非临床红斑狼疮或干燥综合征患者所生者更少见,容易误诊,但只要提高认识,根据典型的临床表现,结合母婴实验室检查,以及组织病理学改变,并经与相关疾病进行鉴别,可以确诊。
[Abstract]:Objective: to improve the quality of diagnosis and treatment of neonatal lupus erythematosus. Methods: the clinical records of 2 cases of neonatal lupus erythematosus from patients with non-clinical lupus erythematosus or Sjogren syndrome were analyzed and summarized, and the etiology, clinical features, histopathological features of the disease were discussed. Diagnosis, differential diagnosis and treatment. Results: according to the characteristics of skin rash in 2 newborns, the diagnosis of neonatal lupus erythematosus was established by the diagnosis of neonatal lupus erythematosus. Conclusion: neonatal lupus is rare in clinic, especially in patients with non-clinical lupus erythematosus or Sjogren's syndrome. And histopathological changes, and can be diagnosed by differentiating with related diseases.
【学位授予单位】：广西医科大学
【学位级别】：硕士
【学位授予年份】：2012
【分类号】：R722.1

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