西安市2010-2015年空气污染对出生缺陷影响的时间序列分析

发布时间：2018-03-07 08:10

  本文选题：空气污染　切入点：二氧化硫(SO)　出处：《西安交通大学学报(医学版)》2017年03期 　论文类型：期刊论文

【摘要】：目的研究西安市空气污染物二氧化硫(SO_2)、二氧化氮(NO_2)和PM_(10)对出生缺陷的影响。方法从西安市妇幼保健院获得西安市2010-2015年出生缺陷监测资料,从西安市环境监测站获得同期空气污染资料,从西安市气象站获得同期气象监测资料,采用广义相加模型控制长期趋势、季节、气温和相对湿度影响,探讨空气污染物与出生缺陷的相关性。结果研究期间西安市月平均出生缺陷达89例;SO_2、NO_2、PM_(10)月平均密度分别是34.05、45.13、96.77μg/m~3;月平均温度为13.57℃;相对湿度为63.20%。在广义相加泊松回归模型(GAM)中,空气污染物SO_2、NO_2、PM_(10)与出生缺陷有关且有一定的滞后效应,均在临产前10月的效应达到最大值,各污染物密度每增加10μg/m~3,RR(95%CI)分别为:1.060(1.023~1.097)、1.033(1.014~1.052)和1.018(1.007~1.029),且差异均具有统计学意义(P0.05)。结论西安市空气污染物SO_2、NO_2、PM_(10)与出生缺陷的发生相关。
[Abstract]:Objective to study the effect of air pollutant sulfur dioxide so _ 2 (no _ 2) and PMSP _ (10) on birth defects. Methods the monitoring data of birth defects in Xi'an from 2010 to 2015 were obtained from Xi'an Maternal and Child Health Hospital. Air pollution data were obtained from Xi'an environmental monitoring station and meteorological monitoring data from Xi'an meteorological station during the same period. The effects of long-term trends, seasons, air temperature and relative humidity were controlled by generalized additive model. To investigate the correlation between air pollutants and birth defects. Results during the study period, the average monthly densities of 89 cases of birth defects in Xi'an were 34.05 / 45.1396.77 渭 g / m ~ (-1) respectively; the monthly mean temperature was 13.57 鈩，

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