118例小儿肺部疾病临床和病理组织检查回顾性分析

发布时间：2018-04-11 09:38

本文选题：病理组织检查 + 肺部疾病　；参考：《重庆医科大学》2017年硕士论文

【摘要】：目的:探讨肺组织病理检查在儿童肺部疾病诊断中的临床价值分析。方法:选取2011年10月至2015年6月经外科手术后行肺组织病理检查的118例有肺部疾病患儿为研究对象,回顾性分析其临床特点、影像学表现、手术方式、术中所见、术前诊断、病理组织检查及出院诊断,评估肺组织病理检查在儿童肺部疾病诊断、鉴别诊断中的临床意义并分析术前未确诊原因。结果:(1)入组的118例,男79例(66.9%),女39例(33.1%),手术年龄3天~15岁3月,手术中位数年龄61月。(2)118例术后均获得病理组织,通过病理检查115例明确诊断。另外3例仅描述镜下炎症细胞浸润或纤维组织增生玻变、红细胞渗出,未做出明确诊断。肺部疾病以先天性肺囊性疾病最常见,见于87例患儿,其次为支气管扩张,见于19例患儿,再为肿瘤5例、肺不张3例、肺结核1例、特发性肺含铁血黄素沉着症及支气管肺前肠畸形各1例。(3)术前诊断与出院诊断符合73例(61.9%),术后病理诊断与出院诊断符合115(97.5%)。结论:病理组织检查对小儿肺部疾病诊断符合率高,对于长期反复诊断不清的肺部疾病,经临床医生评估后,可选择性运用临床。
[Abstract]:Objective: to investigate the clinical value of lung histopathology in the diagnosis of pulmonary diseases in children.Methods: from October 2011 to June 2015, 118 cases of children with pulmonary diseases underwent pathological examination of lung tissue from October 2011 to June 2015. The clinical features, imaging manifestations, operative methods, intraoperative findings and preoperative diagnosis were retrospectively analyzed.Histopathological examination and discharge diagnosis were performed to evaluate the clinical significance of lung histopathological examination in the diagnosis of pulmonary diseases in children and to analyze the causes of undiagnosed diseases before operation.Results among the 118 cases, 79 cases were male and 39 cases were 33. 1%. The operative age was 3 days to 15 months, and the median age of operation was 61 months. All the 118 cases got pathological tissue after operation, and 115 cases were diagnosed by pathological examination.The other 3 cases only described the infiltration of inflammatory cells or fibrous tissue hyperplasia, red blood cell exudation under the microscope, and no definite diagnosis was made.The most common pulmonary diseases were congenital cystic pulmonary diseases, which were seen in 87 cases, followed by bronchiectasis, 19 cases, tumor 5 cases, atelectasis 3 cases, pulmonary tuberculosis 1 case.Idiopathic pulmonary hemosiderosis (n = 1) and bronchopulmonary foregut malformation (n = 1, respectively.) the preoperative diagnosis and discharge diagnosis were in accordance with 73 cases (61.9%), and the postoperative pathological diagnosis and discharge diagnosis were in line with 115% 97. 5%.Conclusion: histopathological examination has a high diagnostic coincidence rate for pulmonary diseases in children, and can be selectively used in the diagnosis of lung diseases which have been repeatedly diagnosed for a long time after assessment by clinicians.
【学位授予单位】：重庆医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R725.6

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