肉眼血尿对尿液化验结果的影响

发布时间：2018-04-14 04:32

本文选题：肉眼血尿 + 尿蛋白定量　；参考：《临床儿科杂志》2017年08期

【摘要】：目的探讨肉眼血尿对尿液多项化验检查结果的影响。方法回顾分析比较2014年1月至2015年12月间收治的80例有明显肉眼血尿的IgA肾病(IgAN)患儿、40例急性链球菌感染后肾小球肾炎(APSGN)患儿,分别在肉眼血尿期间、肉眼血尿消失后送检尿常规、尿蛋白定量、尿白蛋白定量、尿蛋白/肌酐、尿钙定量、尿钙/肌酐、肾早期损伤指标和尿蛋白电泳的变化情况。结果 IgAN和APSGN两组患儿在肉眼血尿期间的尿蛋白定量、尿蛋白/肌酐、尿钙定量、尿钙/肌酐和尿小分子蛋白百分比水平较肉眼血尿消失后明显升高,差异均有统计学意义(P均0.05);而尿白蛋白定量、肾早期损伤各指标(如微量白蛋白、α1微球蛋白水平、N-乙酰-β-D-葡萄糖苷酶)、血钙/肌酐、尿白蛋白百分比水平与肉眼血尿消失后比较,差异均无统计学意义(P均0.05)。肉眼血尿期间,IgAN和APSGN两组患儿的尿蛋白定量水平均高于尿白蛋白定量水平(P0.001);而肉眼血尿消失后,两组患儿的尿蛋白定量与尿白蛋白定量水平之间的差异均无统计学意义(P0.05)。结论肉眼血尿时尿蛋白、尿钙定量结果均偏高,而尿白蛋白定量则不受影响。
[Abstract]:Objective to investigate the effect of naked hematuria on the results of multiple tests in urine.Methods from January 2014 to December 2015, 80 cases of IgA nephropathy with obvious gross hematuria and 40 cases of acute streptococcal glomerulonephritis were retrospectively analyzed and compared during the period of gross hematuria.Urine routine examination, urinary protein quantification, urinary albumin quantification, urinary protein / creatinine, urinary calcium quantitative, urinary calcium / creatinine, early renal injury index and urinary protein electrophoresis after the disappearance of naked hematuria.Results the urinary protein, urine protein / creatinine, urine calcium, urine calcium / creatinine and urinary small molecule protein percentage in IgAN and APSGN group were significantly higher than those in naked eye hematuria group.The differences were statistically significant (P < 0.05), while urinary albumin quantification, early renal injury indexes (such as microalbumin, 伪 1-microglobulin level) N-acetyl- 尾 -Dglucosidase, serum calcium / creatinine,There was no significant difference between urinary albumin percentage and naked hematuria after disappearance (P < 0.05).The levels of urinary protein in the two groups were higher than those in the control group (P 0.001) during the period of gross hematuria, but there was no significant difference between the two groups after the disappearance of gross hematuria (P 0.05).Conclusion the quantitative results of urinary protein and calcium in naked hematuria were higher than those of urinary albumin.
【作者单位】：河北省儿童医院肾脏免疫科;北京大学第一医院儿科;
【分类号】：R726.9

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