乌鲁木齐市新生儿脐血与孕母血维生素D水平的相关性及其影响因素

发布时间：2018-04-21 09:13

本文选题：孕妇 + 新生儿　；参考：《新疆医科大学》2017年硕士论文

【摘要】：目的:了解乌鲁木齐市水磨沟区新生儿脐带血与孕母妊娠末期血维生素D水平的相关性,探讨影响新生儿脐血维生素D水平的相关因素。方法:对自2015年11月至2016年3月冬季我院收住的112例新生儿脐血及其中112例的孕母产前静脉血采用化学发光法测定维生素D值,进行相关性分析。结果:112例新生儿脐血25(OH)D平均水平为(6.75±3.59)ng/ml,112例孕母静脉血25(OH)D平均水平与对应的新生儿脐血25(OH)D水平呈显著正相关(r=0.86,P0.001);新生儿维生素D均处于缺乏状态,受检对象中无维生素D达到20ng/ml者,中、重度维生素D缺乏新生儿占85.7%。汉族孕妇维生素D水平高于维吾尔族孕妇(P0.035),孕母妊娠末期补钙大于3个月的,新生儿脐血维生素D水平高于补钙时间小于3个月者(P0.05);孕妇文化程度越高,维生素D水平越高(P0.027),孕母海产品摄入大于4次/月的,新生儿维生素D水平高于摄入小于4次/月者(P0.021)。孕妇不同孕周、工作类型、户外活动时间、孕期是否抽筋及新生儿胎产次、胎儿性别、出生方式等对新生儿维生素D水平的影响差异无统计学意义(P0.05)。结论:1、新生儿脐血维生素D水平与孕妇妊娠末期维生素D水平呈正相关;2、孕妇民族、文化程度、孕期补钙及海产品摄入影响新生儿脐血维生素D水平;3、水磨沟区孕妇妊娠末期及新生儿冬季维生素D缺乏严重,应给予孕妇末期补充维生素D,以提高孕妇、胎儿及新生儿维生素D水平。
[Abstract]:Objective: to understand the correlation between the blood vitamin D level of newborn umbilical cord blood and pregnancy at the end of pregnancy in Shuimogou District of Urumqi, and to discuss the related factors affecting the level of vitamin D in the umbilical cord blood of the newborn. Methods: 112 cases of newborn umbilical blood collected from November 2015 to March 2016 in our hospital and 112 cases of pregnant mother venous blood were used. The value of vitamin D was measured by the method of luminescence. Results: the average level of 25 (OH) D of umbilical cord blood in 112 newborns was (6.75 + 3.59) ng/ml, and the average level of 25 (OH) D in 112 cases of pregnant female venous blood was positively correlated with the corresponding level of umbilical cord blood 25 (OH) D (r=0.86, P0.001) in the corresponding newborn, and the vitamin D in the newborn was in a lack state, and there was no dimension in the subject. In the patients with 20ng/ml D, the vitamin D in the severe vitamin D deficiency was higher than that of the Uygur pregnant women (P0.035), the calcium supplementation at the end of pregnancy was more than 3 months, and the level of vitamin D in the umbilical cord blood of the newborn was higher than that of the 3 months (P0.05), the higher the maternal culture, the higher the vitamin D level (P0.027). The intake of pregnant women was more than 4 times / month, and the vitamin D level in newborns was higher than that of those who were less than 4 times / month (P0.021). There was no significant difference in the effects of pregnant women, work type, outdoor activity time, pregnancy and neonatal pregnancy, fetal sex and birth mode on the level of neonatal vitin D (P0.05). Conclusion: 1, There is a positive correlation between vitamin D level of newborn umbilical cord blood and vitamin D level of pregnant women at the end of pregnancy; 2, pregnant women's nationality, educational level, calcium supplementation during pregnancy and seafood intake affect vitamin D level in newborn umbilical cord blood; 3, vitamin D deficiency at the end of pregnancy and neonatal winter in Shuimogou district should be supplemented by vitamin D at the end of pregnant women, in order to increase the level of vitamin D Vitamin D levels in pregnant women, fetuses and neonates.

【学位授予单位】：新疆医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R722.1

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