中西药结合治疗婴幼儿支气管肺炎抗生素相关性腹泻的临床疗效观察

发布时间：2018-04-22 15:09

本文选题：中西医结合治疗 + 婴幼儿　；参考：《中成药》2017年05期

【摘要】：目的探讨中西药结合治疗婴幼儿支气管肺炎抗生素相关性腹泻的临床疗效。方法采用回顾性总结方法,2013年7月—2015年7月选择在河北省中医院诊治的婴幼儿支气管肺炎抗生素相关性腹泻96例,根据入院顺序分为观察组与对照组各48例,对照组给予常规西药治疗,在此基础上观察组加用中药制剂醒脾养儿颗粒口服治疗,2组都治疗观察7 d。结果治疗后观察组与对照组的有效率分别为97.9%和87.5%,观察组的疗效明显好于对照组。观察组的腹泻次数减少时间与大便成形时间分别为(2.15±0.34)d和(42.45±7.24)h,而对照组分别为(3.68±0.24)d和(75.22±8.13)h,组间对比差异明显。治疗后2组的血清胃动素(motilin,MOT)和胃泌素(gastrin,GAS)含有量都明显低于治疗前,同时治疗后观察组的血清GAS与MOT含有量也明显低于对照组。结论中西药结合治疗婴幼儿支气管肺炎抗生素相关性腹泻能促进临床症状的恢复和减少血清胃肠激素的分泌,提高治疗疗效,且不会增加经济负担。
[Abstract]:Objective to investigate the clinical effect of combination of traditional Chinese medicine and western medicine in the treatment of antibiotic-associated diarrhea in infants with bronchopneumonia. Methods from July 2013 to July 2015, 96 cases of antibiotic associated diarrhea with bronchopneumonia were selected and treated in Hebei Provincial traditional Chinese Medicine Hospital. According to the order of admission, 96 cases were divided into observation group and control group, 48 cases in each group. The control group was treated with routine western medicine, and the observation group was treated with traditional Chinese medicine Xingpi Yanger granule for 7 days. Results the effective rates of the observation group and the control group were 97.9% and 87.5%, respectively. The curative effect of the observation group was better than that of the control group. The times of diarrhea reduction and stool shaping time were 2.15 卤0.34 and 42.45 卤7.24 hours in the observation group, and 3.68 卤0.24 days and 75.22 卤8.13 hs in the control group, respectively. The difference between the two groups was significant. After treatment, the serum motilin motilint (mot) and gastrin gastrin gastrin (gastrin GAS) contents in the two groups were significantly lower than those before treatment, and the serum GAS and MOT levels in the observation group were also significantly lower than those in the control group after treatment. Conclusion the combination of traditional Chinese medicine and western medicine can promote the recovery of clinical symptoms and decrease the secretion of serum gastrointestinal hormones in infants with bronchopneumonia associated diarrhea and improve the curative effect without increasing economic burden.
【作者单位】：河北省中医院儿科;河北省胸科医院胸外科;
【基金】：河北省2013年医学科学研究课题(20130445)
【分类号】：R725

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