糖皮质激素在先天性肌性斜颈中应用的有效性和安全性研究

发布时间：2018-04-23 13:01

本文选题：糖皮质激素类 + 斜颈/先天性　；参考：《现代医药卫生》2014年09期

【摘要】：目的评价糖皮质激素在先天性肌性斜颈(CMT)中应用的有效性和安全性。方法选择该院2011年1月至2013年1月门诊收治的100例CMT患儿(失访3例,均为对照组,因自行不来复诊被排除),采用严格的纳入标准和单盲随机分配原则,将其分为对照组(47例)和观察组(50例):对照组采用手法治疗,包括按摩、旋转和牵伸的混合治疗的方法;观察组采用糖皮质激素配合手法治疗的方法。随访8个月至1年。结果对照组共收治47例患儿,痊愈15例,临床治愈19例,治愈率为72.3%;无效13例,转手术治疗。观察组共收治50例患儿,痊愈36例,临床治愈11例,治愈率为94.0%;无效3例,转手术治疗。观察组治愈率明显高于对照组,差异有统计学意义(P0.05)。结论早期使用糖皮质激素配合手法治疗能够明显提高CMT患儿的治愈率,家长依从性高,临床上值得推广。
[Abstract]:Objective to evaluate the efficacy and safety of glucocorticoid in the use of congenital muscular torticollis (CMT). Methods 100 children with CMT from January 2011 to January 2013 in the hospital were selected to be divided into control group by strict admission criteria and single blind random distribution principle. (47 cases) and observation group (50 cases): the control group was treated with manipulation, including massage, rotation and drafting. The observation group was treated with glucocorticoid with manipulation. The follow-up group was followed up for 8 months to 1 years. Results the control group treated 47 cases, cured 15 cases, 19 cases were cured, the cure rate was 72.3%, and 13 cases were null and void, and the operation was treated in 13 cases. In the observation group, 50 cases were cured, 36 cases were cured, 11 cases were cured, the cure rate was 94%, and 3 cases were invalid. The cure rate of the observation group was significantly higher than that of the control group. The difference was statistically significant (P0.05). Conclusion early use of glucocorticoid and manipulation can obviously improve the cure rate of children with CMT, high parental compliance, clinical value. It has to be promoted.

【作者单位】：重庆医科大学附属儿童医院骨一科;
【分类号】：R363

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