青海省三个地区乙型肝炎病毒表面抗原阳性母亲所生婴儿免疫后血清学检测现状

发布时间：2018-04-25 05:41

本文选题：乙型肝炎 + 乙型肝炎疫苗　；参考：《中国疫苗和免疫》2017年05期

【摘要】：目的掌握青海省乙型肝炎(乙肝)病毒表面抗原(HBsAg)阳性母亲所生婴儿乙肝疫苗(HepB)免疫后血清学检测(Post-vaccination serological test,PVST)现状,分析影响PVST开展的因素。方法在城市、农村、牧区选择6个县(区)12家医院,对2015年所有HBsAg阳性母亲的婴儿开展PVST回顾性调查,对医院产科医生和当地接种门诊医生开展PVST知晓情况调查。结果共调查HBsAg阳性母亲的婴儿276名,其中35名(12.68%)完成HepB免疫后开展了PVST;城市、农村、牧区PVST检测率分别为14.17%、12.31%、8.06%(χ~2=1.76,P0.05)。Logistic回归分析显示,市级及以上医院出生、母亲为全职职业的婴儿PVST检测率高。在241名未开展PVST婴儿的母亲中,47.72%未收到医生告知,32.78%担心费用,11.62%觉得没必要,7.88%认为孩子太小不愿抽血。在154名产科、接种门诊医生中,56名(36.4%)、19名(12.34%)分别曾口头、书面告知HBsAg阳性母亲开展婴儿PVST。结论 HBsAg阳性母亲婴儿完成HepB免疫后PVST检测率低。产科、接种门诊医生的PVST知晓率低。需加强对家长的宣传和医务人员的培训,以提高婴儿PVST检测率。
[Abstract]:Objective to investigate the status of hepatitis B vaccine hepatitis B vaccine born to infants born to mothers with HBsAg positive in Qinghai province and to analyze the factors influencing the development of PVST. Methods 12 hospitals in 6 counties were selected in urban, rural and pastoral areas. PVST survey was carried out among all the infants of HBsAg positive mothers in 2015, and the knowledge of PVST among obstetricians in hospitals and local vaccination outpatients were investigated. Results A total of 276 infants from mothers with HBsAg positive were investigated, 35 of them (12.68) were tested for PVST after the completion of HepB immunization, and the detection rates of PVST in urban, rural and pastoral areas were 14.171712.31 and 8.06 respectively (蠂 ~ (2 / 2) 1.76) (P 0.05). Logistic regression analysis showed that hospitals at city level and above were born. The rate of PVST detection was high in infants whose mothers were in full-time occupation. Of the 241 mothers without PVST, 47.72% did not receive medical advice, 32.78% were worried about the cost, 11.62% did not feel necessary and 7.88% thought the child was too young to take blood. Out of 154 obstetrics, 56 out of outpatients (56 out of 36.4) were informed orally and in writing to carry out HBsAg in their infants. Conclusion the PVST detection rate of HBsAg positive mothers and infants after HepB immunization is low. In obstetrics, the awareness rate of PVST in vaccinated outpatients was low. In order to improve the rate of PVST detection, parents and medical staff should be trained.
【作者单位】：中国疾病预防控制中心;青海省疾病预防控制中心;
【分类号】：R186

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